{"id":"W2175045519","doi":"10.1039/c5mt00218d","title":"FecB, a periplasmic ferric-citrate transporter from E. coli, can bind different forms of ferric-citrate as well as a wide variety of metal-free and metal-loaded tricarboxylic acids","year":2015,"lang":"en","type":"article","venue":"Metallomics","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Alberta Innovates - Health Solutions","keywords":"Periplasmic space; Chemistry; Ferric; Metal; Transporter; Citric acid; Biochemistry; Inorganic chemistry; Organic chemistry; Escherichia coli","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000572075,0.0007637077,0.002318,0.0003745262,0.00008401719,0.00003895454,0.0005022711,0.0004207015,0.0002982083],"category_scores_gemma":[0.00006940557,0.0005610944,0.0007149656,0.00061338,0.0003608615,0.0002055599,0.00005893397,0.000527068,0.00001843098],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001376801,"about_ca_system_score_gemma":0.000588235,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001049328,"about_ca_topic_score_gemma":0.0008935251,"domain_scores_codex":[0.996008,0.0001086297,0.001359073,0.0008152837,0.001012598,0.0006963703],"domain_scores_gemma":[0.9972731,0.0001032592,0.000559037,0.001051019,0.0002770589,0.0007364865],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.009684279,0.002646338,0.01529518,0.001055793,0.006580953,0.0005195929,0.007488836,0.00008675611,0.9507693,0.004815985,0.0001429899,0.0009139815],"study_design_scores_gemma":[0.02415318,0.002990527,0.03642497,0.0003803122,0.009425062,0.0001124845,0.002954929,0.0008007752,0.8937412,0.02328509,0.004321533,0.001409967],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99053,0.001887097,0.001548964,0.0003872218,0.0003801413,0.001166435,0.000354897,0.00008592119,0.003659343],"genre_scores_gemma":[0.9940562,0.0007178935,0.001797133,0.0003646538,0.00005088542,0.00007200633,0.0002755397,0.0001191688,0.002546543],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05702814,"threshold_uncertainty_score":0.999684,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01868085990163855,"score_gpt":0.2321642019269186,"score_spread":0.2134833420252801,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}