{"id":"W2175229748","doi":"10.1016/j.tibs.2015.08.010","title":"Many Light Touches Convey the Message","year":2015,"lang":"en","type":"review","venue":"Trends in Biochemical Sciences","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research","keywords":"Signal transducing adaptor protein; Phosphorylation; Ubiquitin; Chemistry; Cytoplasm; Cell biology; Glycosylation; Biophysics; Biology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007362247,0.0003015791,0.000532192,0.0001116342,0.00008450619,0.00004814033,0.0008472104,0.0004180194,0.00009421317],"category_scores_gemma":[0.00003052465,0.0001728435,0.000292014,0.0006376621,0.0005043306,0.000003599772,0.0001249254,0.0002308731,0.00001910064],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002831863,"about_ca_system_score_gemma":0.0001464944,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000216318,"about_ca_topic_score_gemma":0.00002613132,"domain_scores_codex":[0.99826,0.00009861329,0.0003866273,0.0006075102,0.0003040253,0.0003432686],"domain_scores_gemma":[0.9993611,0.00001907278,0.0001360941,0.0003611109,0.0000258872,0.00009673367],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002189652,0.0001452604,0.0001085463,0.0008725472,0.00008753782,0.00001915544,0.0001101679,8.894788e-7,0.01400194,0.0005098636,0.01586558,0.9682566],"study_design_scores_gemma":[0.00009180321,0.00006128461,0.000008940939,0.000326075,0.00007167149,0.00001389449,0.00002093446,0.000003244154,0.001623944,0.00004602458,0.9974706,0.000261631],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005113269,0.9908503,0.00002569986,0.0001907257,0.0001821734,0.0001304116,0.00002110043,0.00001119791,0.00807703],"genre_scores_gemma":[0.001677622,0.9946588,0.00005820999,0.00004686508,0.000290153,0.00004262217,0.001623861,0.00001710107,0.001584777],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.981605,"threshold_uncertainty_score":0.7048352,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06190049081623535,"score_gpt":0.342825678399938,"score_spread":0.2809251875837027,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}