{"id":"W2175251478","doi":"10.1212/wnl.84.14_supplement.p7.234","title":"Five-Year Follow-up of Delayed-Release Dimethyl Fumarate in RRMS: Integrated Clinical Efficacy Data from the DEFINE, CONFIRM, and ENDORSE Studies (P7.234)","year":2015,"lang":"en","type":"article","venue":"Neurology","topic":"Fungal Plant Pathogen Control","field":"Agricultural and Biological Sciences","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Dimethyl fumarate; Chemistry; Medicine; Immunology; Multiple sclerosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008385605,0.0001731243,0.0004739183,0.00001290243,0.00005548862,0.00001805786,0.0006182495,0.000166931,0.00004411427],"category_scores_gemma":[0.002803741,0.00005975562,0.00005483806,0.0002044745,0.0003094465,0.0000860936,0.0004116212,0.0003971018,0.00004831159],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004348218,"about_ca_system_score_gemma":0.00002621196,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002500625,"about_ca_topic_score_gemma":0.01890399,"domain_scores_codex":[0.9978617,0.0007177054,0.0004855999,0.0005255227,0.0001459185,0.0002635243],"domain_scores_gemma":[0.9945432,0.004833022,0.0001708112,0.0002303144,0.0001100406,0.0001126456],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0167756,0.0008283627,0.8037809,0.000009225814,0.0004720776,0.0005380428,0.000658106,0.00005304121,0.1150167,0.0006026305,0.02584528,0.03542003],"study_design_scores_gemma":[0.01319416,0.009333427,0.9066206,0.00004499779,0.000332416,0.00008140054,0.001070412,0.005024297,0.0006279064,0.001750951,0.06121626,0.0007031563],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945511,0.00164784,9.147238e-7,0.002140186,0.0004616065,0.0002752758,0.0008003465,0.00002670436,0.00009600131],"genre_scores_gemma":[0.9978493,0.0002613841,0.0000297074,0.001376849,0.0001567525,0.000006946063,0.0002838149,0.000001734227,0.00003353236],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1143888,"threshold_uncertainty_score":0.9989985,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1216756279466835,"score_gpt":0.3141445346267871,"score_spread":0.1924689066801036,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}