{"id":"W2175680311","doi":"10.1021/jo026639y","title":"Dimethylmalonyltrialkylphosphoranes:  New General Reagents for Esterification Reactions Allowing Controlled Inversion or Retention of Configuration on Chiral Alcohols","year":2003,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Organophosphorus compounds synthesis","field":"Chemistry","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brock University","funders":"","keywords":"Chemistry; Steric effects; Reagent; Walden inversion; Triethylamine; Phosphorane; Carboxylic acid; Condensation reaction; Organic chemistry; Solvent; Combinatorial chemistry; Computational chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001076431,0.0002489832,0.000557787,0.00004632109,0.0001798016,0.000043837,0.0003785008,0.0002191041,0.002046616],"category_scores_gemma":[0.002188106,0.0001763927,0.0003258141,0.0002067851,0.00005841067,0.0001729,0.00001823424,0.0003016057,0.000006336033],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002565161,"about_ca_system_score_gemma":0.0004308522,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001600715,"about_ca_topic_score_gemma":0.000001445088,"domain_scores_codex":[0.9978601,0.00008866764,0.001158924,0.0001980216,0.0004681582,0.0002260811],"domain_scores_gemma":[0.9968355,0.0006605809,0.001607199,0.0004788868,0.0002879792,0.0001298037],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004180141,0.0001410431,0.00004375206,0.000105759,0.0002505655,0.000002485136,0.0001959687,0.00004309951,0.9932792,0.00002795413,0.0008872838,0.0008427012],"study_design_scores_gemma":[0.006730897,0.000107923,0.00002935279,0.0002399547,0.0004685897,0.00009858606,0.00049634,0.00008976835,0.9890771,0.0003061867,0.002181949,0.0001733725],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958418,0.0002729315,0.001285708,0.0004002253,0.0003315857,0.0002663356,0.00001074901,0.0000256292,0.001565017],"genre_scores_gemma":[0.9901528,0.0003261571,0.001120206,0.00003301818,0.0003095595,0.000006699847,0.00001964945,0.00005164075,0.007980308],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006415291,"threshold_uncertainty_score":0.9988657,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03392637224800119,"score_gpt":0.2605701689721068,"score_spread":0.2266437967241056,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}