{"id":"W2176052250","doi":"10.1371/journal.pone.0138529","title":"SseK3 Is a Salmonella Effector That Binds TRIM32 and Modulates the Host’s NF-κB Signalling Activity","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Health and Medical Research Council; Medical Research Council; Australian Cancer Research Foundation","keywords":"Effector; Immunoprecipitation; Salmonella; Type three secretion system; Cell biology; Ubiquitin ligase; Death domain; Biology; Ubiquitin; Secretion; Chemistry; Biochemistry; Apoptosis; Genetics; Gene; Bacteria; Programmed cell death; Mutant","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009568789,0.0002756029,0.0001895973,0.0001435083,0.0002014666,0.000272282,0.0001635684,0.0003508299,0.001710044],"category_scores_gemma":[0.00008977688,0.00009341331,0.000398961,0.0001303215,0.0001220053,0.0002128395,0.0002786883,0.0003829674,0.0006750359],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003774263,"about_ca_system_score_gemma":0.0001434396,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003566914,"about_ca_topic_score_gemma":0.0004632566,"domain_scores_codex":[0.9999059,0.00001123874,0.000008686417,0.00002324676,0.00002514723,0.00002572269],"domain_scores_gemma":[0.9999471,0.000004868384,0.00001686638,0.00000524244,0.000008440992,0.00001758556],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001188264,0.00001247246,0.0005675604,0.00004076865,0.000006444388,0.0001053508,0.00001182901,0.00005035385,0.9980757,0.00007168699,0.00004993326,0.0008890903],"study_design_scores_gemma":[0.00002359084,0.0001734501,0.01995448,0.0000128363,0.00002377035,0.001212688,0.00006626608,0.002062308,0.9713833,0.0001058727,0.004971226,0.00001024832],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943002,0.00157388,0.002377439,0.00008987268,0.00001952109,0.00001500085,0.0003669243,0.00007468456,0.001182476],"genre_scores_gemma":[0.9953114,0.0004383335,0.001279365,0.00005861163,0.00000559542,0.00001042683,0.0007896522,0.00001054179,0.002096126],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001710044,"threshold_uncertainty_score":0.005720735,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07815522925314403,"score_gpt":0.2426585040554446,"score_spread":0.1645032748023005,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}