{"id":"W2176476489","doi":"10.2337/db15-0472","title":"Direct Endothelial Nitric Oxide Synthase Activation Provides Atheroprotection in Diabetes-Accelerated Atherosclerosis","year":2015,"lang":"en","type":"article","venue":"Diabetes","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"National Health and Medical Research Council; Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"Enos; Diabetes mellitus; Endothelial dysfunction; Nitric oxide; Oxidative stress; Caveolin 1; Internal medicine; Endogeny; Endocrinology; Nitric Oxide Synthase Type III; Nitric oxide synthase; Endothelial activation; Medicine; Endothelium; Pharmacology; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002613879,0.0002194425,0.0003063932,0.0001370452,0.0001247246,0.0001844392,0.0001388466,0.0002577682,0.001382437],"category_scores_gemma":[0.0001309504,0.0001097097,0.0001489553,0.000114948,0.0002076042,0.0001756484,0.0002059984,0.0006871449,0.0001684196],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009947368,"about_ca_system_score_gemma":0.0001464177,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001328834,"about_ca_topic_score_gemma":0.0002731208,"domain_scores_codex":[0.9999328,0.00002276073,0.000006375053,0.00001138226,0.00001143114,0.00001529749],"domain_scores_gemma":[0.9999404,0.00001138558,0.00001333512,0.000007622346,0.000004363799,0.00002288518],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002718597,0.0005013167,0.0009513401,0.0002110158,0.00002545015,0.0002280598,0.00003030312,0.00007935705,0.9761533,0.0005492131,0.0002045657,0.01834756],"study_design_scores_gemma":[0.001228491,0.01411873,0.05711962,0.00009430468,0.0002629042,0.002505757,0.00008903139,0.001858085,0.9047374,0.00104484,0.01691379,0.0000270504],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9842876,0.009696197,0.002477699,0.0003129757,0.0001321015,0.00003912754,0.00007283808,0.00006822825,0.002913173],"genre_scores_gemma":[0.9915713,0.004826973,0.001667162,0.0001431758,0.00005402113,0.00002643538,0.00008520839,0.000007048892,0.001618716],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001382437,"threshold_uncertainty_score":0.004624724,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03837797889711533,"score_gpt":0.2611148565332527,"score_spread":0.2227368776361373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}