{"id":"W2176476489","doi":"10.2337/db15-0472","title":"Direct Endothelial Nitric Oxide Synthase Activation Provides Atheroprotection in Diabetes-Accelerated Atherosclerosis","year":2015,"lang":"en","type":"article","venue":"Diabetes","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"National Health and Medical Research Council; Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"Enos; Diabetes mellitus; Endothelial dysfunction; Nitric oxide; Oxidative stress; Caveolin 1; Internal medicine; Endogeny; Endocrinology; Nitric Oxide Synthase Type III; Nitric oxide synthase; Endothelial activation; Medicine; Endothelium; Pharmacology; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006849384,0.0002985227,0.0005145678,0.0004233083,0.00006826759,0.0000576151,0.0001073744,0.0001856681,0.00004456677],"category_scores_gemma":[0.001336524,0.0002562844,0.0001181058,0.0009305911,0.00006220534,0.0003093907,0.00003783452,0.0002882672,0.000140319],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002992384,"about_ca_system_score_gemma":0.0001265412,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002301181,"about_ca_topic_score_gemma":0.000005767742,"domain_scores_codex":[0.9980453,0.0001969819,0.0003788063,0.0004333394,0.0003814459,0.0005641446],"domain_scores_gemma":[0.9988301,0.0002909591,0.0001447648,0.0003401124,0.0001570838,0.0002369822],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001226334,0.0002963375,0.2279594,0.0001015531,0.00005425753,0.000003710547,0.0001434201,0.00005642863,0.7655814,0.000004343378,0.0002120476,0.005464473],"study_design_scores_gemma":[0.00344391,0.0004301888,0.09727656,0.0003748454,0.00007331269,0.000001130222,0.0001258083,0.00195755,0.8950325,0.0001358952,0.0008366504,0.0003116118],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966803,0.0001838701,0.0000271603,0.0001806589,0.0001322211,0.001039945,0.00001507579,0.0002835485,0.001457204],"genre_scores_gemma":[0.9981484,0.00001810117,0.0003602553,0.0003769029,0.0002577831,0.0003707983,0.00003243895,0.00007302941,0.0003622209],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1306828,"threshold_uncertainty_score":0.9999889,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03837797889711533,"score_gpt":0.2611148565332527,"score_spread":0.2227368776361373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}