{"id":"W2176662837","doi":"10.1089/vim.2015.0036","title":"Heteroclitic Peptides Increase Proliferation and Reduce Evidence of Human Immunodeficiency Virus-Specific CD8 <sup>+</sup> T Cell Dysfunction","year":2015,"lang":"en","type":"article","venue":"Viral Immunology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Canadian Institutes of Health Research","keywords":"CD8; Epitope; T cell; Cytotoxic T cell; Biology; Immunology; Cytokine; Virology; Antigen; Molecular biology; Immune system; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008556326,0.0002133051,0.0001532216,0.00009660749,0.00006824367,0.0001439415,0.00009824123,0.0001510041,0.0007978947],"category_scores_gemma":[0.0001088059,0.00005702944,0.00008267538,0.00006328861,0.0001374945,0.0001028734,0.00009605633,0.0002463254,0.0001522412],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006225866,"about_ca_system_score_gemma":0.0000501829,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005654208,"about_ca_topic_score_gemma":0.0001374956,"domain_scores_codex":[0.9999266,0.00001717566,0.000005993467,0.00001270001,0.00001852492,0.0000190581],"domain_scores_gemma":[0.9998939,0.00002744196,0.00003451483,0.000009581971,0.000007781311,0.00002677292],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003057879,0.00010671,0.001100323,0.00003289618,0.000007873203,0.0000771871,0.00001664262,0.000128408,0.9925437,0.00002685044,0.00002252739,0.005631038],"study_design_scores_gemma":[0.00008835144,0.0070747,0.02211012,0.000009698404,0.00004539882,0.001769915,0.00008278718,0.0006696052,0.9658224,0.00005883062,0.00226162,0.00000657999],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998893,0.0005037118,0.0002141024,0.000004780385,0.000004039363,0.000009139168,0.00001761483,0.000004669331,0.000349062],"genre_scores_gemma":[0.9988024,0.0002710682,0.0005054255,0.00001928973,0.000008086784,0.000009832538,0.00007148663,0.000003121898,0.0003093299],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007978947,"threshold_uncertainty_score":0.002669215,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04165295102066474,"score_gpt":0.286714625358326,"score_spread":0.2450616743376613,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}