{"id":"W2176704368","doi":"10.1667/0033-7587(2001)156[0272:sttcom]2.0.co;2","title":"Sensitization to the Cytotoxicity of Melphalan by Ethacrynic Acid and Hyperthermia in Drug-Sensitive and Multidrug-Resistant Chinese Hamster Ovary Cells","year":2001,"lang":"en","type":"article","venue":"Radiation Research","topic":"Insect and Pesticide Research","field":"Agricultural and Biological Sciences","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chinese hamster ovary cell; Sensitization; Melphalan; Cytotoxicity; Hyperthermia; Pharmacology; Drug; Multiple drug resistance; Ovary; In vitro; Chemistry; Cell culture; Medicine; Biology; Drug resistance; Chemotherapy; Immunology; Biochemistry; Microbiology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001457831,0.00009032815,0.0001366004,0.00006234309,0.0002036183,0.0000595964,0.0001011194,0.00006933427,0.00007040887],"category_scores_gemma":[0.0002870349,0.00003483132,0.00002037973,0.0007596194,0.0001003716,0.00008734621,0.00008692612,0.0002221528,0.00001248702],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003767617,"about_ca_system_score_gemma":0.00001512156,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003150615,"about_ca_topic_score_gemma":0.005212469,"domain_scores_codex":[0.9982432,0.0006270881,0.0001731231,0.0002365401,0.0004157873,0.0003042196],"domain_scores_gemma":[0.9985607,0.001080892,0.00003221464,0.000061955,0.0001538986,0.0001103241],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000163511,0.00004123241,0.01729061,0.000009739992,0.000004976767,0.000008463811,0.0008874879,0.00001355774,0.9647996,0.0000238176,0.0004512159,0.01630573],"study_design_scores_gemma":[0.0002796559,0.0001697174,0.9106858,0.00002555165,0.000002090357,0.000007782563,0.000628964,0.003289589,0.08391161,0.0001883854,0.0006940447,0.0001168289],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931974,0.0002261264,0.0000029628,0.005633901,0.00001528997,0.0004734266,0.00004934168,0.00000690911,0.0003946807],"genre_scores_gemma":[0.9990124,0.0004525311,0.00001832427,0.000119012,0.00008557925,0.00001571503,0.00002660779,0.000001570779,0.0002683263],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8933952,"threshold_uncertainty_score":0.4762809,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02323242791256389,"score_gpt":0.2959500027697197,"score_spread":0.2727175748571558,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}