{"id":"W2176727624","doi":"10.1667/0033-7587(2002)157[0149:pockbl]2.0.co;2","title":"Potentiation of Cell Killing by Low-Dose-Rate Radiation by Camptothecin is Related to an Increase in the Level of DNA Double-Strand Breaks","year":2002,"lang":"en","type":"article","venue":"Radiation Research","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University; Health Canada; Ottawa Regional Cancer Foundation","funders":"National Cancer Institute","keywords":"Camptothecin; Radiosensitivity; Irradiation; Long-term potentiation; DNA damage; Chemistry; Dose–response relationship; Biophysics; Pharmacology; Toxicology; Biology; Molecular biology; DNA; Biochemistry; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001182719,0.00008956546,0.0001109041,0.0001343162,0.00006643255,0.00002534183,0.0001981491,0.0001407413,0.00009373787],"category_scores_gemma":[0.00002747472,0.00008135141,0.00004172113,0.0003546314,0.00003197259,0.00001217196,0.00001953282,0.000124814,0.000005321847],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003713529,"about_ca_system_score_gemma":0.00004855871,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006348186,"about_ca_topic_score_gemma":0.00005640821,"domain_scores_codex":[0.9986587,0.0002604935,0.0002938158,0.0002444746,0.0003271365,0.0002154298],"domain_scores_gemma":[0.9993436,0.00004181835,0.0001072451,0.0002858583,0.0001491711,0.00007235378],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001619559,0.0001814986,0.0001541802,0.00001945555,0.00001545924,2.974057e-7,0.0009217698,0.0002238791,0.9851909,0.00004874668,0.002675446,0.01040645],"study_design_scores_gemma":[0.001838512,0.0003448301,0.001154404,0.00001096209,0.000008175084,6.92791e-7,0.0002125332,0.003778097,0.9878629,0.0001011254,0.004587958,0.00009974284],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968786,0.0007379244,0.0008200264,0.0005297688,0.00003884806,0.0004521061,0.0002103995,0.000002760624,0.0003295569],"genre_scores_gemma":[0.9976935,0.0010444,0.00004967194,0.0001793309,0.00003110918,0.00002877666,0.0002784114,0.00001623396,0.000678502],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0103067,"threshold_uncertainty_score":0.3317414,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05586858068286907,"score_gpt":0.3327095867040543,"score_spread":0.2768410060211852,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}