{"id":"W2176727624","doi":"10.1667/0033-7587(2002)157[0149:pockbl]2.0.co;2","title":"Potentiation of Cell Killing by Low-Dose-Rate Radiation by Camptothecin is Related to an Increase in the Level of DNA Double-Strand Breaks","year":2002,"lang":"en","type":"article","venue":"Radiation Research","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University; Health Canada; Ottawa Regional Cancer Foundation","funders":"National Cancer Institute","keywords":"Camptothecin; Radiosensitivity; Irradiation; Long-term potentiation; DNA damage; Chemistry; Dose–response relationship; Biophysics; Pharmacology; Toxicology; Biology; Molecular biology; DNA; Biochemistry; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001641757,0.000410589,0.0004295105,0.0001836189,0.00009272074,0.0002197276,0.0001533265,0.0002249451,0.002115442],"category_scores_gemma":[0.0002538174,0.0001531375,0.0003198942,0.0001663844,0.0002132081,0.0001476784,0.0001514505,0.0006920851,0.0005305196],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002185436,"about_ca_system_score_gemma":0.0001494774,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003702902,"about_ca_topic_score_gemma":0.0005125052,"domain_scores_codex":[0.9997821,0.00004815983,0.00001916452,0.00004243533,0.00007417861,0.00003391833],"domain_scores_gemma":[0.9997372,0.00008985375,0.00005676611,0.00004612984,0.0000376462,0.00003237806],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006967781,0.00002333507,0.0001445626,0.00002936337,0.000003430904,0.00001306902,0.00001219544,0.00004589418,0.9989409,0.00001348998,0.0000115131,0.0006925633],"study_design_scores_gemma":[0.000008387568,0.0006247745,0.00723074,0.000005309421,0.00001013271,0.00009817172,0.0000138041,0.0003420509,0.9909989,0.00001363482,0.0006510837,0.000003056397],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930502,0.00212917,0.002310454,0.00009172867,0.00003120563,0.00006003105,0.0003210126,0.00007000946,0.001936118],"genre_scores_gemma":[0.9942233,0.001134411,0.002110431,0.00005000073,0.00001625661,0.00004896069,0.0004553422,0.00002236425,0.00193904],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002115442,"threshold_uncertainty_score":0.0070768,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05586858068286907,"score_gpt":0.3327095867040543,"score_spread":0.2768410060211852,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}