{"id":"W2176746879","doi":"10.1093/molbev/msv272","title":"Direct Estimate of the Spontaneous Mutation Rate Uncovers the Effects of Drift and Recombination in the <i>Chlamydomonas reinhardtii</i> Plastid Genome","year":2015,"lang":"en","type":"article","venue":"Molecular Biology and Evolution","topic":"Evolution and Genetic Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Biotechnology and Biological Sciences Research Council","keywords":"Plastid; Biology; Genome; Genetics; Mutation Accumulation; Mutation rate; Genome evolution; Mutation; Chlamydomonas reinhardtii; Nuclear gene; Evolutionary biology; Gene; Chloroplast; Mutant","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008209516,0.0003044394,0.0003096431,0.0006516799,0.0002182866,0.0002679376,0.0003626286,0.000319961,0.0003524057],"category_scores_gemma":[0.001858121,0.0001928958,0.0003020283,0.0002666825,0.0002548863,0.0001847051,0.0003307778,0.0004041138,0.000108851],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000399949,"about_ca_system_score_gemma":0.0001714818,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001761301,"about_ca_topic_score_gemma":0.002232908,"domain_scores_codex":[0.9995311,0.00007344427,0.00003222115,0.0002107004,0.0001114291,0.0000410951],"domain_scores_gemma":[0.9987637,0.0004835878,0.0002652553,0.0002762275,0.0001315005,0.00007984371],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001393212,0.0001010638,0.1737907,0.00007747,0.0002238733,0.0001295847,0.0001410916,0.004218626,0.8052412,0.0007160811,0.00008038024,0.01514075],"study_design_scores_gemma":[0.00001666271,0.0003909313,0.6815139,0.00002468284,0.0001905723,0.0008241895,0.0001391336,0.04711911,0.2681339,0.0006599901,0.0009390676,0.00004786861],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912356,0.0003196984,0.007879676,0.00001253105,0.000004375571,0.00001136055,0.0002017613,0.00006012032,0.0002748193],"genre_scores_gemma":[0.9952702,0.00009545211,0.004251031,0.00001520267,0.000001987345,0.00001373562,0.0002571953,0.00001047651,0.00008473703],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001761301,"threshold_uncertainty_score":0.004341662,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002906356863706415,"score_gpt":0.2277311432999178,"score_spread":0.2248247864362114,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}