{"id":"W2177193625","doi":"10.1089/10430340360464732","title":"Gene Transfer to Subdermal Tissues via a New Gene Gun Design","year":2003,"lang":"en","type":"article","venue":"Human Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institutes of Health; National Cancer Institute; Vector Institute; Dow Chemical Company","keywords":"Gene gun; Genetic enhancement; Gene; Gene expression; Gene delivery; Biology; Plasmid; Molecular biology; DNA vaccination; Cancer research; Cell biology; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005545925,0.0004325297,0.0003296155,0.0001464593,0.000266699,0.00007384499,0.0005692117,0.0002380346,0.001207827],"category_scores_gemma":[0.00001300774,0.0004255721,0.0001929445,0.0002454414,0.00008957383,0.000007843204,0.00004071122,0.0001625399,0.0001931809],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004228876,"about_ca_system_score_gemma":0.0002517941,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005008219,"about_ca_topic_score_gemma":0.0001246343,"domain_scores_codex":[0.9972191,0.0004293723,0.0003614812,0.0007904154,0.0003922113,0.0008074524],"domain_scores_gemma":[0.9984111,0.00001370808,0.00002753656,0.0009726653,0.0001268983,0.0004481403],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001670897,0.0001529543,0.00006507677,0.000003636465,0.0001775108,0.00002344455,0.0003165141,0.0004814433,0.9828219,0.00002162141,0.002890126,0.0113749],"study_design_scores_gemma":[0.002215259,0.005128349,0.0001698974,0.000003808687,0.00001179225,0.00005244122,0.00001238679,0.000007946848,0.9583135,0.0002964895,0.03327846,0.0005097283],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9449062,0.007216285,0.04630237,0.0001996716,0.0001106934,0.0008863938,0.00001363587,0.00005462634,0.0003101008],"genre_scores_gemma":[0.9843226,0.001625355,0.006781144,0.002204432,0.0008003102,0.0001324853,0.0001384264,0.0001835499,0.003811705],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03952123,"threshold_uncertainty_score":0.9998196,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05364282269554212,"score_gpt":0.3227785243534366,"score_spread":0.2691357016578945,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}