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Pardee Foundation; Instituto de Salud Carlos III; National Research Foundation of Korea; Pancreatic Cancer Action Network; Breast Cancer Research Foundation; Univerzita Karlova v Praze; National Institute of Diabetes and Digestive and Kidney Diseases; Gilead Sciences; National Institute on Alcohol Abuse and Alcoholism; University of New South Wales; Natural Environment Research Council; University of Glasgow; U.S. Department of Veterans Affairs; Grantová Agentura České Republiky; United Soybean Board","keywords":"Broad spectrum; Tumor microenvironment; Cancer; Mechanism (biology); Personalized medicine; Computational biology; Medicine; Bioinformatics; Disease; Cancer therapy; Precision medicine; Biology; Cancer research; Internal medicine; Chemistry; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004085653,0.0007518826,0.0007891072,0.001653895,0.001248423,0.002459105,0.001410533,0.001343468,0.006292531],"category_scores_gemma":[0.00169686,0.0003707443,0.001276455,0.0008017971,0.00182853,0.002602672,0.003986662,0.00328524,0.001854604],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001900074,"about_ca_system_score_gemma":0.005699465,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001167337,"about_ca_topic_score_gemma":0.002901861,"domain_scores_codex":[0.998489,0.0006085892,0.00007626981,0.0002838236,0.0003796682,0.0001625709],"domain_scores_gemma":[0.9992011,0.000188297,0.00009137844,0.00009973312,0.0002331842,0.0001862277],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0003442782,0.001299616,0.004310693,0.005400955,0.0004599793,0.0005612563,0.002296273,0.006828919,0.0664097,0.1351699,0.02655141,0.7503671],"study_design_scores_gemma":[0.0003032054,0.002683981,0.005692651,0.002631807,0.0006891607,0.00116535,0.002792477,0.00638259,0.02109755,0.1206661,0.8357775,0.0001176435],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"review","genre_scores_codex":[0.06483874,0.1424612,0.5762282,0.08046567,0.004155106,0.003774631,0.0006137488,0.001351152,0.1261116],"genre_scores_gemma":[0.345904,0.1230932,0.4707252,0.02589531,0.00138394,0.003640834,0.0008611893,0.0003303925,0.02816597],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.006292531,"threshold_uncertainty_score":0.02160728,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1242781234996095,"score_gpt":0.4522328012984213,"score_spread":0.3279546777988118,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). 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