{"id":"W217783584","doi":"10.1007/s40259-015-0126-5","title":"Status and Prospects of Aptamers as Drug Components","year":2015,"lang":"en","type":"review","venue":"BioDrugs","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"Carleton University","funders":"","keywords":"Aptamer; Drug; Pharmacotherapy; Medicine; Computational biology; Intensive care medicine; Pharmacology; Biology; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007594556,0.000885843,0.001087516,0.001514747,0.0002132235,0.001304371,0.000923675,0.001356839,0.00305885],"category_scores_gemma":[0.0007364229,0.0003975669,0.0004541581,0.001652485,0.0006723086,0.001898309,0.0009749611,0.00153683,0.001900206],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004665286,"about_ca_system_score_gemma":0.0006729593,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005054082,"about_ca_topic_score_gemma":0.0007939542,"domain_scores_codex":[0.9997757,0.00003543435,0.00002465191,0.00005170725,0.0000809449,0.00003159129],"domain_scores_gemma":[0.9996934,0.0001699047,0.00004815675,0.00001274832,0.00005112677,0.00002474008],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009534609,0.00009992984,0.0002321687,0.009581142,0.00005012105,0.0002114373,0.00006963771,0.0006597606,0.01110663,0.009535737,0.01067048,0.9576877],"study_design_scores_gemma":[0.00001649538,0.0001392623,0.0004474849,0.001153384,0.00007739222,0.0009227245,0.00005049969,0.0003071009,0.004274088,0.003681891,0.9889059,0.00002377374],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002988923,0.9978573,0.000455123,0.0001634348,0.0001274946,0.000003756729,0.00001267702,0.000006742679,0.001074545],"genre_scores_gemma":[0.002009017,0.9956785,0.0006467375,0.0002507254,0.0001857044,0.000008679986,0.00002805249,0.000002530697,0.001190053],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00305885,"threshold_uncertainty_score":0.01023287,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02908022629780935,"score_gpt":0.335241854693982,"score_spread":0.3061616283961726,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}