{"id":"W2178037542","doi":"10.1089/104303401750061212","title":"Interleukin 12 Gene Transfer into Skin Distant from the Tumor Site Elicits Antimetastatic Effects Equivalent to Local Gene Transfer","year":2001,"lang":"en","type":"article","venue":"Human Gene Therapy","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"U.S. Army Medical Research Acquisition Activity; Vector Institute","keywords":"Cancer research; Genetic enhancement; CD8; Gene delivery; Transfection; Metastasis; Primary tumor; Monoclonal antibody; Antibody; Immunotherapy; Biology; Pathology; Immunology; Molecular biology; Medicine; Cancer; Immune system; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008505669,0.000396264,0.0002437503,0.0001918316,0.00008775319,0.0002220748,0.00009818316,0.000241121,0.001020989],"category_scores_gemma":[0.00007894012,0.0001123979,0.0002608514,0.00007834595,0.0002374081,0.0001514583,0.0001096224,0.0007266686,0.0002310756],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001293689,"about_ca_system_score_gemma":0.0001365243,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002289588,"about_ca_topic_score_gemma":0.0003406076,"domain_scores_codex":[0.9998808,0.00001704894,0.000006708423,0.00003141461,0.00002965636,0.00003434963],"domain_scores_gemma":[0.9999062,0.00002429118,0.00002307493,0.00001463371,0.000009205457,0.00002263034],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002829545,0.00002645113,0.00003347501,0.0000128139,0.000001520894,0.00001557949,0.000004093963,0.00003798461,0.9993948,0.00001432686,0.000005540669,0.000425016],"study_design_scores_gemma":[0.00001272353,0.0007472174,0.0007350217,0.000002300126,0.00001216947,0.00009427075,0.000008664413,0.0004130034,0.9975511,0.0000118628,0.0004100773,0.000001615052],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948623,0.0009434322,0.003015867,0.00004673607,0.00003149482,0.00002661646,0.0000629714,0.00007279948,0.0009377089],"genre_scores_gemma":[0.9965883,0.0005167429,0.001450862,0.0000291183,0.00001550763,0.00002437047,0.000101668,0.00001154634,0.001261848],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001020989,"threshold_uncertainty_score":0.003415585,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01701093582350914,"score_gpt":0.2561163510895585,"score_spread":0.2391054152660493,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}