{"id":"W2178784291","doi":"10.1016/j.cell.2015.10.068","title":"CD5L/AIM Regulates Lipid Biosynthesis and Restrains Th17 Cell Pathogenicity","year":2015,"lang":"en","type":"article","venue":"Cell","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":401,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; National Human Genome Research Institute; Klarman Cell Observatory, Broad Institute; National Cancer Institute; National Institutes of Health; Multiple Sclerosis Society of Canada; National Institute of Allergy and Infectious Diseases; Broad Institute; Howard Hughes Medical Institute; Crohn's and Colitis Foundation of America; National Multiple Sclerosis Society","keywords":"Biology; Cell biology; Regulator; Autoimmunity; Transcription factor; Immune system; Cell; Lipid metabolism; Immunology; Genetics; Gene; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002741134,0.0003626767,0.0002042479,0.0003725457,0.0003112579,0.0007612413,0.0004176526,0.0004936309,0.002769729],"category_scores_gemma":[0.0002144239,0.0002125495,0.0003022861,0.000113107,0.0003668682,0.0003446967,0.0005950876,0.001083667,0.0008241012],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007294807,"about_ca_system_score_gemma":0.000326001,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007015293,"about_ca_topic_score_gemma":0.001493135,"domain_scores_codex":[0.9996119,0.00006457722,0.00002347477,0.00004887536,0.00007782682,0.0001733392],"domain_scores_gemma":[0.9998515,0.00001255465,0.0000429849,0.00001542765,0.00001733555,0.00006017085],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004834934,0.00006126796,0.002095596,0.00006232949,0.00001371963,0.0001897248,0.00002517134,0.0001589813,0.9924328,0.0005436374,0.0003474501,0.003585771],"study_design_scores_gemma":[0.00008805584,0.0004366076,0.04442921,0.00003581977,0.00007122681,0.0005593328,0.000302465,0.002992667,0.9412491,0.0004425736,0.009376075,0.00001675379],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9878136,0.003724692,0.003055161,0.0004271289,0.0001332041,0.00002646783,0.0003404711,0.0001917607,0.004287475],"genre_scores_gemma":[0.9953643,0.0003974409,0.001132333,0.000139667,0.0000203225,0.00001376603,0.0002418118,0.00002034426,0.002670044],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002769729,"threshold_uncertainty_score":0.009265721,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0183760252228128,"score_gpt":0.2122452205167665,"score_spread":0.1938691952939537,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}