{"id":"W2179075701","doi":"10.3390/act4040267","title":"Role of α and β Transmembrane Domains in Integrin Clustering","year":2015,"lang":"en","type":"article","venue":"Actuators","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"","keywords":"Integrin; Transmembrane protein; Biophysics; Transmembrane domain; Signal transduction; Cell biology; Molecular dynamics; Dimer; Protein subunit; Chemistry; Computational biology; Biology; Cell; Membrane; Biochemistry; Receptor; Gene; Computational chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008941461,0.00007888654,0.0001071423,0.00003795721,0.000007716188,0.000004296703,0.00007107607,0.00008278263,0.000004541296],"category_scores_gemma":[0.00002273845,0.00006685063,0.00002579697,0.00004977851,0.00004273234,0.000003289538,0.00003647804,0.00005344848,9.042033e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005356015,"about_ca_system_score_gemma":0.00003332787,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005793721,"about_ca_topic_score_gemma":0.0002259477,"domain_scores_codex":[0.9995492,0.00001756051,0.000121686,0.0001400562,0.00006249125,0.000109046],"domain_scores_gemma":[0.9997557,0.000004103947,0.00002658434,0.0001291271,0.00001896165,0.00006552642],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006647283,0.00001950772,0.008558182,0.00001319361,0.000008033253,0.000001380957,0.0005007856,0.0000101647,0.974086,0.00003227907,0.00001883836,0.01668514],"study_design_scores_gemma":[0.001099193,0.0001864697,0.008128152,0.00001488349,0.00001545086,0.00002151311,0.000774246,0.00004279454,0.9828194,0.00009533107,0.006660636,0.0001419397],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988883,0.0001244767,0.0001055948,0.0000251046,0.00005142141,0.00007276331,0.000004458199,0.000003947319,0.000723922],"genre_scores_gemma":[0.9994503,0.00003529013,0.0003411645,0.00003974365,0.00005920023,0.000004135183,0.00001609124,0.000009292825,0.00004481864],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0165432,"threshold_uncertainty_score":0.2726089,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00997813863951599,"score_gpt":0.2471776603498098,"score_spread":0.2371995217102938,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}