{"id":"W2179075701","doi":"10.3390/act4040267","title":"Role of α and β Transmembrane Domains in Integrin Clustering","year":2015,"lang":"en","type":"article","venue":"Actuators","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"","keywords":"Integrin; Transmembrane protein; Biophysics; Transmembrane domain; Signal transduction; Cell biology; Molecular dynamics; Dimer; Protein subunit; Chemistry; Computational biology; Biology; Cell; Membrane; Biochemistry; Receptor; Gene; Computational chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001839494,0.0001492686,0.0002216029,0.0002304155,0.0004392697,0.0004784063,0.0002794168,0.0005083837,0.0006981711],"category_scores_gemma":[0.0009107787,0.0001971367,0.0002093066,0.0001766033,0.0004636145,0.0004209631,0.0002701233,0.0001818778,0.0001183311],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003984542,"about_ca_system_score_gemma":0.000406739,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002969719,"about_ca_topic_score_gemma":0.002244127,"domain_scores_codex":[0.9998986,0.00002659674,0.00000535269,0.00002233297,0.00002135568,0.00002574916],"domain_scores_gemma":[0.9997662,0.00007458979,0.00005130086,0.00002076774,0.00002696084,0.00006026747],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000755856,0.0002186253,0.01892693,0.0003444304,0.0000987762,0.0009438078,0.0007207763,0.4653891,0.4625231,0.02738632,0.0007781155,0.02191418],"study_design_scores_gemma":[0.00006737772,0.0001409831,0.02068396,0.00002845111,0.00004462953,0.0001966604,0.0003004504,0.935019,0.03670966,0.005458202,0.001296506,0.00005413259],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907787,0.0006416067,0.006409955,0.0001296883,0.00001305271,0.00001225776,0.00001871001,0.00004205739,0.001954039],"genre_scores_gemma":[0.9987858,0.0001189583,0.0008831476,0.00001191985,0.000001348323,0.000003527251,0.000008870012,0.000004177612,0.0001822799],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002969719,"threshold_uncertainty_score":0.005904853,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00997813863951599,"score_gpt":0.2471776603498098,"score_spread":0.2371995217102938,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}