{"id":"W2179172619","doi":"10.1667/0033-7587(2001)156[0002:fmiptg]2.0.co;2","title":"Frameshift Mutation in<i>PRKDC</i>, the Gene for DNA-PKcs, in the DNA Repair-Defective, Human, Glioma-Derived Cell Line M059J","year":2001,"lang":"en","type":"article","venue":"Radiation Research","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institute of General Medical Sciences","keywords":"Frameshift mutation; Exon; Biology; Molecular biology; Gene; Mutation; Genetics; Exon trapping; DNA; DNA-PKcs; genomic DNA; DNA repair; Alternative splicing","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001414687,0.0006985235,0.0003198747,0.0004406968,0.0004292535,0.0003507743,0.0005619182,0.0006683408,0.002422499],"category_scores_gemma":[0.0001511615,0.000292415,0.0007170099,0.0003724468,0.0005974424,0.0001751039,0.0003405225,0.001125762,0.001810119],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006816594,"about_ca_system_score_gemma":0.0003898992,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002272449,"about_ca_topic_score_gemma":0.004437633,"domain_scores_codex":[0.999756,0.00002596903,0.00003744611,0.00006429228,0.00008054436,0.00003575086],"domain_scores_gemma":[0.9997875,0.00003358405,0.00009163983,0.00002478322,0.00001203723,0.00005041823],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001212154,0.00005223162,0.0002690366,0.00005512441,0.00001238095,0.0005503181,0.00003058434,0.00004670248,0.996873,0.0003303899,0.0002873509,0.001371755],"study_design_scores_gemma":[0.00007199778,0.0005286881,0.01298631,0.00003481767,0.00006711578,0.00359595,0.00009905333,0.0006184407,0.9649146,0.00009700129,0.01695994,0.00002611262],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9777322,0.00170857,0.007542909,0.0003593986,0.0004124865,0.000294186,0.005948518,0.0003383245,0.005663401],"genre_scores_gemma":[0.972903,0.001057926,0.008937838,0.0002084589,0.00006330122,0.0001077684,0.007707883,0.0001338291,0.008880026],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002422499,"threshold_uncertainty_score":0.008104086,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03759756662715245,"score_gpt":0.3531031988814308,"score_spread":0.3155056322542783,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}