{"id":"W2179237675","doi":"10.1016/j.molcel.2015.11.006","title":"Targeting Mitosis in Cancer: Emerging Strategies","year":2015,"lang":"en","type":"review","venue":"Molecular Cell","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":496,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network; Ontario Institute for Cancer Research","funders":"Canadian Institutes of Health Research","keywords":"Biology; Mitosis; Cell cycle; Cancer; Cell cycle checkpoint; Computational biology; Genome instability; Cancer research; Bioinformatics; Cell biology; Genetics; DNA damage; DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001002668,0.001163366,0.001736291,0.001941329,0.0004082425,0.001397368,0.001360863,0.00176184,0.002924724],"category_scores_gemma":[0.001024683,0.0004038521,0.0004499221,0.001698587,0.001135021,0.002225495,0.001347595,0.003234118,0.001590405],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001054837,"about_ca_system_score_gemma":0.001192302,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0010847,"about_ca_topic_score_gemma":0.002826375,"domain_scores_codex":[0.9997922,0.00003114366,0.00002265691,0.00003838093,0.00007981397,0.00003587572],"domain_scores_gemma":[0.9996169,0.0001592588,0.00004824164,0.00001258575,0.0001007751,0.00006213898],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001572744,0.00007199228,0.0001616324,0.01273116,0.00007651614,0.0002515521,0.00006132755,0.0007842716,0.002907989,0.010668,0.06066101,0.9114673],"study_design_scores_gemma":[0.00002448843,0.00005911747,0.0003057826,0.00159166,0.00008256133,0.0005780083,0.0000451519,0.0001603986,0.0005944835,0.004087646,0.9924507,0.00001986363],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000673532,0.9984289,0.0002335815,0.0004080739,0.0002639531,0.000003046341,0.00001241619,0.000009033649,0.0005735818],"genre_scores_gemma":[0.000586926,0.9982003,0.000213635,0.0003046594,0.000267448,0.000004719543,0.00002064487,0.000001471592,0.0004000461],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002924724,"threshold_uncertainty_score":0.009784102,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01837834317834443,"score_gpt":0.3073261492278631,"score_spread":0.2889478060495187,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}