{"id":"W2179359065","doi":"10.1371/journal.pone.0131513","title":"High Expression Levels of BLyS/BAFF by Blood Dendritic Cells and Granulocytes Are Associated with B-cell dysregulation in SIV-Infected Rhesus Macaques","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; Université de Montréal","funders":"National Institute of Neurological Disorders and Stroke; Fonds de Recherche du Québec - Santé; National Institutes of Health; Canadian Institutes of Health Research; University of Miami; Styrelsen för Internationellt Utvecklingssamarbete","keywords":"B-cell activating factor; Immunology; Immune system; Simian immunodeficiency virus; B cell; Biology; Lentivirus; Antibody; Virology; Medicine; Virus; Viral disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001128451,0.0001848517,0.0001906048,0.0005710209,0.0002747311,0.0003513524,0.00009225032,0.000242945,0.0006711633],"category_scores_gemma":[0.0001859085,0.000121695,0.0001163384,0.0001566913,0.0002482881,0.0001408842,0.0002488448,0.0003454376,0.0001758824],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001945943,"about_ca_system_score_gemma":0.0001032934,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001274517,"about_ca_topic_score_gemma":0.00142506,"domain_scores_codex":[0.9998775,0.00001313484,0.00001239051,0.00003265445,0.00002320986,0.00004108649],"domain_scores_gemma":[0.9998789,0.00001328464,0.00004351577,0.00001226235,0.00001937034,0.00003263905],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002000633,0.0000162663,0.01390185,0.00002036048,0.000008591386,0.0001520249,0.0001449714,0.00001548104,0.9843873,0.00003485762,0.00002349674,0.001094779],"study_design_scores_gemma":[0.00001275112,0.0004097074,0.7275833,0.00001889381,0.00004775244,0.002195406,0.0005662893,0.0006171477,0.2663836,0.0001894413,0.001961014,0.00001473114],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990022,0.0004142958,0.0001723827,0.00001273083,0.00000174289,0.000007192128,0.0001430934,0.00001050833,0.0002358796],"genre_scores_gemma":[0.9986703,0.0002171973,0.0003715561,0.00002964567,0.000004322122,0.00002347793,0.0002578813,0.000005852986,0.0004197535],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001274517,"threshold_uncertainty_score":0.002534211,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02737077452084093,"score_gpt":0.216459433945034,"score_spread":0.189088659424193,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}