{"id":"W2179775941","doi":"10.1039/c5ra19050a","title":"Codelivery of doxorubicin and p53 by biodegradable micellar carriers based on chitosan derivatives","year":2015,"lang":"en","type":"article","venue":"RSC Advances","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Drug Research and Development","funders":"National Natural Science Foundation of China","keywords":"Chitosan; Doxorubicin; Micelle; Cationic polymerization; Chemistry; Combinatorial chemistry; Polymer chemistry; Organic chemistry; Chemotherapy; Aqueous solution; Surgery; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001537694,0.0005409002,0.0002001268,0.0002528066,0.0001127259,0.0002873295,0.0002401256,0.0004100259,0.0006735862],"category_scores_gemma":[0.0002408536,0.0001418695,0.0002534578,0.0001762268,0.0003034015,0.0004745913,0.000240124,0.0003794992,0.0002748739],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004394637,"about_ca_system_score_gemma":0.0003250303,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001098762,"about_ca_topic_score_gemma":0.00167437,"domain_scores_codex":[0.9998884,0.00001249644,0.0000116136,0.00002652904,0.00003220611,0.00002876716],"domain_scores_gemma":[0.9998569,0.00002174854,0.00005852081,0.000010691,0.00002637752,0.000025683],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004282304,0.00000877191,0.00005298753,0.00004455895,0.000003485387,0.00007448043,0.000009387858,0.00007272921,0.9979615,0.000135553,0.00002628617,0.001567517],"study_design_scores_gemma":[0.00001118627,0.0001043406,0.0003050778,0.000003738529,0.00001050224,0.0001119658,0.000005016484,0.0005462485,0.9974935,0.00001667821,0.001385449,0.000006348655],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9745592,0.004949322,0.01786936,0.0002975991,0.00008629257,0.000108922,0.0001075019,0.0001645537,0.00185719],"genre_scores_gemma":[0.9877484,0.001791999,0.007515213,0.00008444421,0.00002186202,0.00004512905,0.00009047048,0.00003023785,0.002672184],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001098762,"threshold_uncertainty_score":0.00318855,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01155099279138995,"score_gpt":0.2455263381560977,"score_spread":0.2339753453647077,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}