{"id":"W2179882789","doi":"10.4049/jimmunol.1500378","title":"Regulation of TLR3 Activation by S100A9","year":2015,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval; Centre hospitalier universitaire de Québec","funders":"National Institute of General Medical Sciences; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"TLR3; Endosome; Cell biology; Innate immune system; Biology; Chemistry; Intracellular; Toll-like receptor; Immune system; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001174914,0.00008268622,0.0002233103,0.0001313129,0.00006100455,0.00000324026,0.0002480402,0.0001703004,0.0001237754],"category_scores_gemma":[0.0003282484,0.00005380751,0.00006175237,0.0001213159,0.000200621,0.0002073891,0.00003730517,0.0002631687,0.00007534029],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005289332,"about_ca_system_score_gemma":0.0001162207,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003887195,"about_ca_topic_score_gemma":7.460168e-7,"domain_scores_codex":[0.9986174,0.0006338891,0.0005203829,0.00004399476,0.00004997017,0.0001343238],"domain_scores_gemma":[0.9984264,0.0002263625,0.0007851779,0.0001888015,0.0003651879,0.000008097584],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001740035,0.00004599462,0.0000682412,0.000002484405,0.0001841135,2.003547e-7,0.00104767,0.00003543576,0.9790996,0.0004611952,0.01198221,0.005332855],"study_design_scores_gemma":[0.001422613,0.000691024,0.005786808,0.00002766989,0.0000482572,0.0002654669,0.0008648072,0.000004221541,0.9550529,0.0008201597,0.03495948,0.00005666418],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9904675,0.005295349,0.001570234,0.001358289,0.0006015497,0.00008008409,0.000001201153,0.000007933997,0.0006178914],"genre_scores_gemma":[0.998426,0.0002236764,0.00003626559,0.00004634667,0.00002720059,8.049149e-7,0.00001534444,0.000007068267,0.001217271],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02404673,"threshold_uncertainty_score":0.2194207,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01425403829521995,"score_gpt":0.2336413520625425,"score_spread":0.2193873137673226,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}