{"id":"W2180280763","doi":"10.1016/j.chom.2015.10.017","title":"Attacking the Supply Lines: HIV-1 Restricts Alanine Uptake to Prevent T Cell Activation","year":2015,"lang":"en","type":"letter","venue":"Cell Host & Microbe","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Biology; Human immunodeficiency virus (HIV); Alanine; Serine; Cell; Transporter; Immunity; Virology; Cell biology; Immune system; Amino acid; Immunology; Biochemistry; Gene; Phosphorylation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0003451818,0.0006180728,0.000561964,0.0002681329,0.0003411385,0.00009605564,0.0008867963,0.001077743,0.0009900035],"category_scores_gemma":[0.00007952592,0.0004325514,0.0002290195,0.0003185323,0.0001466566,0.00007799025,0.0004063985,0.002201492,0.0189466],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003641707,"about_ca_system_score_gemma":0.0004598517,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002516266,"about_ca_topic_score_gemma":0.00002675702,"domain_scores_codex":[0.996922,0.0004570025,0.0005210335,0.0008181622,0.0001584045,0.001123444],"domain_scores_gemma":[0.998,0.0003160429,0.000277612,0.001050554,0.0002684254,0.00008736422],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000665368,0.0002177609,0.00009510499,0.00008217312,0.0001239842,0.0001054215,0.0004705392,0.000004864465,0.2249431,5.116391e-7,0.7733551,0.0005349414],"study_design_scores_gemma":[0.0009732953,0.0002908434,0.000259165,0.0001165493,0.00009275948,0.00003523806,0.00008303806,2.450818e-7,0.1935884,0.000004441447,0.8042188,0.0003371901],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"other","genre_scores_codex":[0.1784445,0.02051631,0.0002420004,0.7652087,0.003702478,0.007365976,0.00441275,0.0004331808,0.01967407],"genre_scores_gemma":[0.09506334,0.001103588,0.0004645729,0.269413,0.003961622,0.0007287666,0.04507068,0.0004140827,0.5837803],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.5641062,"threshold_uncertainty_score":0.9999232,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02254002596639968,"score_gpt":0.2615066908897101,"score_spread":0.2389666649233105,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}