{"id":"W2180280763","doi":"10.1016/j.chom.2015.10.017","title":"Attacking the Supply Lines: HIV-1 Restricts Alanine Uptake to Prevent T Cell Activation","year":2015,"lang":"en","type":"letter","venue":"Cell Host & Microbe","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Biology; Human immunodeficiency virus (HIV); Alanine; Serine; Cell; Transporter; Immunity; Virology; Cell biology; Immune system; Amino acid; Immunology; Biochemistry; Gene; Phosphorylation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000992965,0.0005297349,0.0006959195,0.0002222856,0.001329231,0.001711245,0.0008225846,0.01467328,0.003751479],"category_scores_gemma":[0.005060044,0.0003572852,0.000604797,0.0001374773,0.001473186,0.001354846,0.0008511668,0.01574507,0.002568057],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001851205,"about_ca_system_score_gemma":0.0007418841,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008442143,"about_ca_topic_score_gemma":0.001363759,"domain_scores_codex":[0.9994227,0.0001722112,0.00005784412,0.00005719628,0.0001612861,0.0001287574],"domain_scores_gemma":[0.9988999,0.0006073367,0.00009490117,0.00008022573,0.0001281267,0.0001894198],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008140372,0.0002321823,0.002351465,0.0001740933,0.00007503801,0.01499776,0.0002480895,0.0004686907,0.0114462,0.02046202,0.877906,0.07082425],"study_design_scores_gemma":[0.00087961,0.0007797782,0.002558028,0.0002104868,0.0000870275,0.01639535,0.0003913167,0.002789753,0.01259916,0.03276256,0.9304513,0.00009573135],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.007493481,0.004953651,0.0007800463,0.9573708,0.02042847,0.00002665412,0.00003665273,0.0001210313,0.008789319],"genre_scores_gemma":[0.1562782,0.005952464,0.001859489,0.7486398,0.05913905,0.00009956519,0.00005782258,0.00005122665,0.0279224],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01467328,"threshold_uncertainty_score":0.01343149,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02254002596639968,"score_gpt":0.2615066908897101,"score_spread":0.2389666649233105,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}