{"id":"W2180481183","doi":"10.1290/1543-706x(2003)039<0340:dstsca>2.0.co;2","title":"DIFFERENTIAL SENSITIVITY TO SHORT-CHAIN CERAMIDE ANALOGUES OF HUMAN INTESTINAL CARCINOMA CELLS GROWN IN TUMOR SPHEROIDS VERSUS MONOLAYER CULTURE","year":2003,"lang":"en","type":"article","venue":"In Vitro Cellular & Developmental Biology - Animal","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Spheroid; Ceramide; Cell culture; Cytotoxic T cell; Cytotoxicity; Cisplatin; Biology; Cell; Toxicity; Monolayer; Molecular biology; Cell biology; Cancer research; In vitro; Biochemistry; Internal medicine; Apoptosis; Medicine; Chemotherapy; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002660828,0.00031191,0.000612893,0.0003334002,0.0002280057,0.0003924325,0.00018711,0.0003338225,0.001992043],"category_scores_gemma":[0.0003304074,0.000213077,0.0003886168,0.0003363186,0.0001748778,0.0003053681,0.0002591639,0.0006407098,0.000696856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003366073,"about_ca_system_score_gemma":0.0002381924,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002149891,"about_ca_topic_score_gemma":0.001559628,"domain_scores_codex":[0.9996833,0.00008804034,0.0000404305,0.00006451301,0.00005741786,0.00006640692],"domain_scores_gemma":[0.9995311,0.0002112559,0.00003634611,0.00008002923,0.00007919128,0.00006195762],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004686381,0.00003043872,0.0002026754,0.00004023272,0.000007179166,0.00005605713,0.00005291539,0.0001031203,0.9981037,0.000032296,0.00005321391,0.0008494894],"study_design_scores_gemma":[0.000006853589,0.0002980573,0.001887685,0.000002435811,0.000009308932,0.00008294809,0.00004283072,0.0002747614,0.9969182,0.00001234624,0.0004620695,0.00000261286],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922556,0.002014343,0.001648206,0.00009422731,0.00008114184,0.00004936789,0.001050405,0.00006571054,0.002741022],"genre_scores_gemma":[0.9904103,0.001393522,0.001966296,0.000065383,0.00002983354,0.00006265601,0.001933356,0.0000403022,0.004098288],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002149891,"threshold_uncertainty_score":0.006664038,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01683350417843908,"score_gpt":0.2492498872070591,"score_spread":0.23241638302862,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}