{"id":"W2180481183","doi":"10.1290/1543-706x(2003)039<0340:dstsca>2.0.co;2","title":"DIFFERENTIAL SENSITIVITY TO SHORT-CHAIN CERAMIDE ANALOGUES OF HUMAN INTESTINAL CARCINOMA CELLS GROWN IN TUMOR SPHEROIDS VERSUS MONOLAYER CULTURE","year":2003,"lang":"en","type":"article","venue":"In Vitro Cellular & Developmental Biology - Animal","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Spheroid; Ceramide; Cell culture; Cytotoxic T cell; Cytotoxicity; Cisplatin; Biology; Cell; Toxicity; Monolayer; Molecular biology; Cell biology; Cancer research; In vitro; Biochemistry; Internal medicine; Apoptosis; Medicine; Chemotherapy; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00035315,0.0003528763,0.000472749,0.0001406474,0.00007652404,0.00001607103,0.0002018097,0.0002558887,0.00002236464],"category_scores_gemma":[0.0001018978,0.0003497803,0.0001176201,0.0002382398,0.0001231232,0.000009151568,0.0001867602,0.000265324,0.00000609445],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007627139,"about_ca_system_score_gemma":0.0001107624,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002060988,"about_ca_topic_score_gemma":0.0002797278,"domain_scores_codex":[0.9978117,0.0003145825,0.0005344941,0.0006600221,0.0001230322,0.0005561864],"domain_scores_gemma":[0.9995008,0.00002920021,0.00008970589,0.0001923947,0.00005852123,0.0001293504],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008949768,0.000296191,0.04557618,0.00001800615,0.00003519203,0.00007945117,0.0003109191,0.00000551141,0.9525209,0.0001015041,0.00002589602,0.0001352684],"study_design_scores_gemma":[0.002231439,0.0004116104,0.01680033,0.0000188627,0.0000159709,0.00002618392,0.0005020497,0.00002982244,0.9792852,0.0000284202,0.0002650305,0.000385062],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984061,0.00027946,0.000367389,0.000007715084,0.0002729364,0.0002644858,0.0000320295,0.00001158521,0.0003582622],"genre_scores_gemma":[0.996055,0.000009575014,0.003402764,0.00007394851,0.0001254591,0.00002258326,0.0002594372,0.00002848918,0.00002272954],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02877585,"threshold_uncertainty_score":0.9998954,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01683350417843908,"score_gpt":0.2492498872070591,"score_spread":0.23241638302862,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}