{"id":"W2180777891","doi":"10.1080/15476286.2015.1094603","title":"Role of lysine binding residues in the global folding of the<i>lysC</i>riboswitch","year":2015,"lang":"en","type":"article","venue":"RNA Biology","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Riboswitch; Ribozyme; Biology; Ligand (biochemistry); Folding (DSP implementation); Binding site; Biophysics; RNA; Aptamer; Biochemistry; Cell biology; Genetics; Non-coding RNA; Gene; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005925404,0.00009612044,0.0001700878,0.0000242306,0.00002761045,0.000003837605,0.0004328988,0.0001532191,0.000005221917],"category_scores_gemma":[0.0002256027,0.00005637068,0.00008110895,0.0001722084,0.00009396346,0.000002007461,0.0001324836,0.00004886317,0.000002141854],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001193705,"about_ca_system_score_gemma":0.00006502423,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001659586,"about_ca_topic_score_gemma":0.000134387,"domain_scores_codex":[0.9990759,0.0002570104,0.0002328209,0.0001735159,0.00008567945,0.0001750866],"domain_scores_gemma":[0.9993902,0.00002667294,0.0001529927,0.0003514273,0.00005375169,0.00002489327],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005441733,0.00002636656,0.03006633,0.000005225982,0.00001944383,3.299518e-7,0.00007322213,0.00000749002,0.9647254,0.002900911,0.00007743716,0.002043363],"study_design_scores_gemma":[0.0002836376,0.000208248,0.003826991,0.00001873222,0.00001317121,0.000009664157,0.0003819249,0.000005834742,0.9841954,0.007113187,0.003867416,0.00007582718],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955784,0.001512529,0.0001373009,0.000276195,0.0001058654,0.0001441073,0.00002254277,0.000002757258,0.002220289],"genre_scores_gemma":[0.9993293,0.00006247032,0.0003722683,0.00009520754,0.00007906844,0.00001053112,0.00001186473,0.000005729683,0.00003355901],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02623934,"threshold_uncertainty_score":0.229873,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01730016683530516,"score_gpt":0.2662671285932426,"score_spread":0.2489669617579375,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}