{"id":"W2180908646","doi":"10.1016/j.bmcl.2004.04.093","title":"Thiourea inhibitors of herpes viruses. Part 2: N-Benzyl-N′-arylthiourea inhibitors of CMV","year":2004,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Cytomegalovirus and herpesvirus research","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Chemistry; Thiourea; Cytomegalovirus; Human cytomegalovirus; IC50; Virus; Enzyme inhibitor; Betaherpesvirinae; Virology; In vitro; Herpesviridae; Stereochemistry; Biochemistry; Viral disease; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002640031,0.0007878908,0.0004252051,0.0009017251,0.0002314689,0.0002138278,0.0005471861,0.0003173287,0.002306388],"category_scores_gemma":[0.0001765998,0.0002699384,0.0005963791,0.0003679223,0.0001768906,0.00031129,0.0002275355,0.0004996074,0.0006263157],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003912931,"about_ca_system_score_gemma":0.0002623261,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001444822,"about_ca_topic_score_gemma":0.002941298,"domain_scores_codex":[0.9999168,0.00001512401,0.00000661849,0.000007414132,0.00001644674,0.00003749726],"domain_scores_gemma":[0.9999549,0.00001429046,0.00001021238,0.000004723746,0.000006151674,0.000009569881],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001497486,0.001062305,0.0005381489,0.001049674,0.0001689137,0.000726438,0.0001965215,0.003534306,0.8034751,0.001508436,0.00610641,0.1801362],"study_design_scores_gemma":[0.00107105,0.01163652,0.00963954,0.0001478059,0.0003812014,0.002459526,0.00005692598,0.002817919,0.8807113,0.0004572899,0.09054852,0.00007227446],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.677163,0.2603359,0.01513641,0.0009437403,0.001602756,0.0007988915,0.001075053,0.0006379343,0.0423063],"genre_scores_gemma":[0.7945651,0.1696847,0.003911025,0.0007110666,0.0007367482,0.000414038,0.001424605,0.00008576307,0.02846693],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002306388,"threshold_uncertainty_score":0.007715702,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02193898272621519,"score_gpt":0.2763663625555084,"score_spread":0.2544273798292933,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}