{"id":"W2181342396","doi":"10.3389/fmicb.2015.01244","title":"Inside the Envelope: Endogenous Retrovirus-K Env as a Biomarker and Therapeutic Target","year":2015,"lang":"en","type":"review","venue":"Frontiers in Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; University of Winnipeg","funders":"University of Winnipeg","keywords":"Endogenous retrovirus; Biology; Epigenetics; Innate immune system; Biomarker; Virology; Disease; Gene silencing; Retrovirus; Genome; Genetics; Gene; Immunology; Immune system; Virus; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003459142,0.0005153301,0.0008263694,0.00122643,0.0001840787,0.0008050369,0.0005088302,0.001011875,0.001886349],"category_scores_gemma":[0.0003647889,0.0001943423,0.0003325913,0.0008391068,0.0004921652,0.0009289653,0.0004152455,0.001734875,0.001146436],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004878829,"about_ca_system_score_gemma":0.0005451643,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004221924,"about_ca_topic_score_gemma":0.0007641118,"domain_scores_codex":[0.9998777,0.00002084841,0.00001536263,0.00002392421,0.00004732975,0.00001482981],"domain_scores_gemma":[0.999858,0.00007595325,0.00001639493,0.000005490001,0.00003165038,0.00001233348],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008101625,0.0000743398,0.0002216673,0.0104989,0.00006385936,0.0004110885,0.00008503703,0.0004009232,0.01458086,0.009068235,0.01989622,0.9446179],"study_design_scores_gemma":[0.000008593998,0.0001008162,0.0004218808,0.001173986,0.00005786305,0.001712715,0.00005147972,0.0001122899,0.00357175,0.002336754,0.9904354,0.00001663555],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002985025,0.9971796,0.0003931131,0.0003806155,0.0002284293,0.000004134001,0.00001586621,0.00001213802,0.001487523],"genre_scores_gemma":[0.002468209,0.9953881,0.0004614212,0.0003052246,0.0001499231,0.000006711801,0.00003307391,0.000003370068,0.001183923],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001886349,"threshold_uncertainty_score":0.006310403,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02727623020795097,"score_gpt":0.3067871858984882,"score_spread":0.2795109556905373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}