{"id":"W2182691378","doi":"10.1128/mbio.01498-15","title":"Gene Loss and Error-Prone RNA Editing in the Mitochondrion of <i>Perkinsela</i> , an Endosymbiotic Kinetoplastid","year":2015,"lang":"en","type":"article","venue":"mBio","topic":"Protist diversity and phylogeny","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Institute for Advanced Research; Dalhousie University","funders":"Canadian Institutes of Health Research; Seventh Framework Programme; Canadian Institute for Advanced Research; Russian Science Foundation; Russian Foundation for Basic Research; Akademie Věd České Republiky; Dalhousie University","keywords":"RNA editing; Biology; Guide RNA; Genetics; RNA; Genome; Mitochondrial DNA; Gene; Computational biology; Genome editing","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001161874,0.0002873095,0.0001923118,0.0002195245,0.0002054983,0.0003417093,0.0002843384,0.0003764724,0.0007679298],"category_scores_gemma":[0.0002997341,0.0001560374,0.0003136401,0.0001629692,0.0002343239,0.0001687541,0.0002717006,0.0003903161,0.0004949638],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003197775,"about_ca_system_score_gemma":0.0001631982,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001235591,"about_ca_topic_score_gemma":0.001829141,"domain_scores_codex":[0.9998721,0.000008070854,0.00001221808,0.00005573889,0.00003186567,0.00001994491],"domain_scores_gemma":[0.9997173,0.00006398994,0.0001055866,0.00003723065,0.00003794549,0.00003794592],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000633645,0.000008523481,0.001480283,0.0000645777,0.00001281363,0.00009328689,0.00003295816,0.0001029999,0.9967229,0.00002507987,0.0000386299,0.00135457],"study_design_scores_gemma":[0.00002286527,0.0004690228,0.1517189,0.00003370445,0.0001550173,0.002083031,0.0002489959,0.003136685,0.8361552,0.0001117769,0.005824283,0.00004047737],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962782,0.0004338769,0.001777483,0.00003235024,0.00001467687,0.00001231948,0.0009613975,0.0001181406,0.0003714954],"genre_scores_gemma":[0.9929222,0.0002304236,0.003253768,0.00005703807,0.000004593007,0.00002123424,0.002185345,0.0000915364,0.00123384],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001235591,"threshold_uncertainty_score":0.00256896,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02182821241796976,"score_gpt":0.2383572390946965,"score_spread":0.2165290266767267,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}