{"id":"W2183009257","doi":"10.4236/oji.2015.55020","title":"Fyn Expression Predicates Both Protective Immunity and Onset of Autoimmunity","year":2015,"lang":"en","type":"article","venue":"Open Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute; Sunnybrook Hospital; University of Toronto","funders":"National Institutes of Health; University of Toronto; Sunnybrook Research Institute","keywords":"FYN; Biology; T cell; Immunology; Cancer research; Autocrine signalling; Autoimmunity; Cell biology; Immune system; Signal transduction; Cell culture; Proto-oncogene tyrosine-protein kinase Src; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001871749,0.0003113058,0.001054149,0.0003258426,0.0002826281,0.00003577914,0.001574632,0.0005704389,0.0004149699],"category_scores_gemma":[0.0006692088,0.0002418994,0.0001377123,0.000222891,0.001512014,0.0004873446,0.001322471,0.001430099,0.00006014995],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008308784,"about_ca_system_score_gemma":0.0005520322,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007355519,"about_ca_topic_score_gemma":0.00001813335,"domain_scores_codex":[0.9963869,0.001735547,0.001075412,0.0002569828,0.00008083809,0.000464353],"domain_scores_gemma":[0.9969837,0.0003677278,0.001399305,0.0006073808,0.0005788493,0.00006304037],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002874779,0.0006416466,0.001904739,0.00001856096,0.0006712185,0.00002796299,0.001989058,0.00000333848,0.9844779,0.0002571593,0.00211396,0.005019649],"study_design_scores_gemma":[0.008584189,0.004842459,0.0115789,0.0002711817,0.0001422325,0.004219784,0.004998234,0.00000177562,0.9382026,0.003762255,0.02305079,0.0003455745],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9759118,0.02004289,0.0002029472,0.0004615491,0.00105529,0.0004963182,0.00003643856,0.00002233785,0.001770454],"genre_scores_gemma":[0.9975451,0.0006833321,0.0006715122,0.00005803084,0.00002108552,0.00001887668,0.00003027043,0.00002625316,0.0009455847],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04627531,"threshold_uncertainty_score":0.9864371,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02751230821003833,"score_gpt":0.2679978680511529,"score_spread":0.2404855598411146,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}