{"id":"W2183009257","doi":"10.4236/oji.2015.55020","title":"Fyn Expression Predicates Both Protective Immunity and Onset of Autoimmunity","year":2015,"lang":"en","type":"article","venue":"Open Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute; Sunnybrook Hospital; University of Toronto","funders":"National Institutes of Health; University of Toronto; Sunnybrook Research Institute","keywords":"FYN; Biology; T cell; Immunology; Cancer research; Autocrine signalling; Autoimmunity; Cell biology; Immune system; Signal transduction; Cell culture; Proto-oncogene tyrosine-protein kinase Src; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000121202,0.0003014421,0.0001716152,0.0002459708,0.0001215094,0.0002828807,0.000127318,0.0003705595,0.001291215],"category_scores_gemma":[0.0001423923,0.0001133703,0.000163928,0.00008595597,0.0002220714,0.0002065306,0.0002045252,0.0006432428,0.0003146815],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003060837,"about_ca_system_score_gemma":0.0002331116,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003024804,"about_ca_topic_score_gemma":0.000460963,"domain_scores_codex":[0.9998729,0.00001464614,0.00001555598,0.00002762798,0.00002487326,0.00004427575],"domain_scores_gemma":[0.9998171,0.00001943429,0.00006085596,0.00001701959,0.00001138408,0.00007412032],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001110277,0.00001233991,0.0002953782,0.00001198249,0.000001509524,0.0000681176,0.00000595348,0.0000222349,0.9986702,0.0000812184,0.0000236803,0.0006962336],"study_design_scores_gemma":[0.00001294346,0.0002664556,0.01005448,0.000008754915,0.00001235212,0.001035827,0.00002636675,0.0005057305,0.9855757,0.0001172969,0.002380279,0.000003980029],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954266,0.0007737944,0.001996078,0.0001044365,0.00002644387,0.00001017439,0.0002685407,0.00006291489,0.001331052],"genre_scores_gemma":[0.9964039,0.0002727051,0.0008946825,0.00003162058,0.000008373026,0.000009028146,0.0002747661,0.00001439906,0.002090647],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001291215,"threshold_uncertainty_score":0.004319549,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02751230821003833,"score_gpt":0.2679978680511529,"score_spread":0.2404855598411146,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}