{"id":"W2184789189","doi":"10.1016/j.abb.2015.11.037","title":"Fungal cobalamin-independent methionine synthase: Insights from the model organism, Neurospora crassa","year":2015,"lang":"en","type":"article","venue":"Archives of Biochemistry and Biophysics","topic":"Porphyrin Metabolism and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"Western Economic Diversification Canada; Canadian Institutes of Health Research; Alberta Science and Research Authority; Natural Sciences and Engineering Research Council of Canada; Alberta Heritage Foundation for Medical Research; U.S. Department of Energy; University of Saskatchewan; National Research Council Canada; University of California; National Institutes of Health; National Science Foundation","keywords":"Neurospora crassa; Cobalamin; Methionine synthase; Biology; Biochemistry; Enzyme; Stereochemistry; Neurospora; Methionine; Protein structure; Conserved sequence; Chemistry; Peptide sequence; Amino acid; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005991614,0.0002135774,0.0001951588,0.00001175001,0.00008645668,0.00002478767,0.0003282357,0.0001089298,0.000001998148],"category_scores_gemma":[0.00008571793,0.0001577463,0.00009332527,0.00007403007,0.0003762293,0.000006789795,0.0002742704,0.0001339822,0.000001787294],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002334308,"about_ca_system_score_gemma":0.0001381382,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004137171,"about_ca_topic_score_gemma":0.000003873955,"domain_scores_codex":[0.9989809,0.00004647044,0.0002080233,0.0003904813,0.0001926827,0.0001813948],"domain_scores_gemma":[0.9991574,0.00004483077,0.0001290539,0.0004710288,0.00004716911,0.0001504998],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001327179,0.0001178743,0.0008297826,0.00001602212,0.00005696604,0.00000319519,0.0001830023,0.00009539888,0.9965484,0.0003929272,0.0004804698,0.001143294],"study_design_scores_gemma":[0.0007109282,0.00007938193,0.001780719,0.0000137069,0.00005924203,0.000005710782,0.0003441194,0.0008795676,0.9890546,0.006024792,0.0008277966,0.0002194744],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930235,0.002775851,0.002235895,0.0001927376,0.00007583564,0.00009230592,0.0001911852,0.00001150399,0.001401255],"genre_scores_gemma":[0.9974262,0.0004828756,0.00104321,0.0002734986,0.0002219875,0.000005834206,0.0002877691,0.00001773114,0.0002408581],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007493788,"threshold_uncertainty_score":0.6432709,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01019887771757965,"score_gpt":0.2187863142550011,"score_spread":0.2085874365374215,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}