{"id":"W2184789189","doi":"10.1016/j.abb.2015.11.037","title":"Fungal cobalamin-independent methionine synthase: Insights from the model organism, Neurospora crassa","year":2015,"lang":"en","type":"article","venue":"Archives of Biochemistry and Biophysics","topic":"Porphyrin Metabolism and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"Western Economic Diversification Canada; Canadian Institutes of Health Research; Alberta Science and Research Authority; Natural Sciences and Engineering Research Council of Canada; Alberta Heritage Foundation for Medical Research; U.S. Department of Energy; University of Saskatchewan; National Research Council Canada; University of California; National Institutes of Health; National Science Foundation","keywords":"Neurospora crassa; Cobalamin; Methionine synthase; Biology; Biochemistry; Enzyme; Stereochemistry; Neurospora; Methionine; Protein structure; Conserved sequence; Chemistry; Peptide sequence; Amino acid; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006639892,0.0003801173,0.0002201386,0.0001856035,0.0002082757,0.0004292316,0.0002361421,0.0003442762,0.0002763976],"category_scores_gemma":[0.0000632134,0.0001014926,0.0001724785,0.0001430928,0.0002793747,0.0003751302,0.0001367236,0.0006660142,0.0001554143],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008066061,"about_ca_system_score_gemma":0.0006430427,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009104664,"about_ca_topic_score_gemma":0.009447934,"domain_scores_codex":[0.9999788,0.000002089585,0.000001651419,0.000004949476,0.000007951441,0.000004581928],"domain_scores_gemma":[0.9999746,0.000004424233,0.000004177147,0.000003480544,0.000004280979,0.000008979896],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002443295,0.00002929792,0.0008383206,0.000178629,0.00001251396,0.0003923622,0.00004494942,0.000834632,0.987641,0.002421387,0.0002210744,0.007141566],"study_design_scores_gemma":[0.0000338943,0.0001717446,0.0103161,0.00005037152,0.0000861841,0.001712085,0.0003584609,0.01043417,0.949886,0.003556624,0.02336922,0.00002508512],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9665897,0.01591657,0.009925956,0.001445809,0.00005535601,0.00001893432,0.0007549112,0.0001348854,0.00515783],"genre_scores_gemma":[0.9812702,0.01029663,0.006282905,0.00008249279,0.00001096591,0.000004141557,0.0005003401,0.00001232966,0.001539981],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009104664,"threshold_uncertainty_score":0.01810336,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01019887771757965,"score_gpt":0.2187863142550011,"score_spread":0.2085874365374215,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}