{"id":"W2184837125","doi":"10.1373/clinchem.2015.243279","title":"A Novel N-Tetrasaccharide in Patients with Congenital Disorders of Glycosylation, Including Asparagine-Linked Glycosylation Protein 1, Phosphomannomutase 2, and Mannose Phosphate Isomerase Deficiencies","year":2015,"lang":"en","type":"article","venue":"Clinical Chemistry","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health","keywords":"Tetrasaccharide; Glycosylation; Glycan; Mannose; Glycoprotein; Asparagine; Biochemistry; Chemistry; Molecular biology; Biology; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000137063,0.0005119511,0.000174103,0.000819554,0.0003218064,0.0003277611,0.0001941965,0.0006717604,0.0008151893],"category_scores_gemma":[0.0003972235,0.0001569104,0.0002147595,0.0004578647,0.0003033277,0.0002401013,0.0002632858,0.0003559315,0.0001280559],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002819728,"about_ca_system_score_gemma":0.0001344164,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001106928,"about_ca_topic_score_gemma":0.0008636297,"domain_scores_codex":[0.9998678,0.00001618686,0.00001598417,0.00005296075,0.00002903715,0.000018006],"domain_scores_gemma":[0.9998305,0.00002625082,0.00006016448,0.0000111237,0.00002127312,0.00005067459],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001470674,0.0001708583,0.6286566,0.00009297047,0.00009430252,0.01721415,0.0005274379,0.0001714262,0.3372549,0.0001036728,0.0002946618,0.01394846],"study_design_scores_gemma":[0.00005190237,0.001110894,0.8435692,0.00002154286,0.00009872069,0.08768738,0.0003791753,0.00118681,0.06434932,0.0001404478,0.001387536,0.00001711802],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994136,0.0001773547,0.0001528956,0.00002317015,0.000003361755,0.000007084966,0.00005369403,0.000009531009,0.0001592741],"genre_scores_gemma":[0.999339,0.00007883098,0.0003541493,0.00003026935,0.000003557532,0.000003792713,0.00009508433,0.000002454933,0.00009278777],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001106928,"threshold_uncertainty_score":0.002727032,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03110455564745018,"score_gpt":0.3024169465348727,"score_spread":0.2713123908874225,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}