{"id":"W2184837125","doi":"10.1373/clinchem.2015.243279","title":"A Novel N-Tetrasaccharide in Patients with Congenital Disorders of Glycosylation, Including Asparagine-Linked Glycosylation Protein 1, Phosphomannomutase 2, and Mannose Phosphate Isomerase Deficiencies","year":2015,"lang":"en","type":"article","venue":"Clinical Chemistry","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health","keywords":"Tetrasaccharide; Glycosylation; Glycan; Mannose; Glycoprotein; Asparagine; Biochemistry; Chemistry; Molecular biology; Biology; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006101641,0.0002396954,0.0002985793,0.0000566524,0.00006406681,0.00003340593,0.0002098563,0.0002576115,0.00002155373],"category_scores_gemma":[0.000972353,0.0002214126,0.00007139472,0.0002958619,0.0003312903,0.00002949071,0.0001969186,0.0002722199,0.000004182838],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003862292,"about_ca_system_score_gemma":0.0002276938,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001070501,"about_ca_topic_score_gemma":0.00009121894,"domain_scores_codex":[0.9979746,0.00005147761,0.0006800955,0.0005593958,0.000408488,0.0003259827],"domain_scores_gemma":[0.9986945,0.00005176161,0.0002571305,0.0003636428,0.000372253,0.0002606967],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003842655,0.00110561,0.9284469,0.0001264876,0.0000940216,0.000005947064,0.000103729,0.0003045901,0.06036389,0.00002599186,0.00007025502,0.00550991],"study_design_scores_gemma":[0.02536641,0.001834368,0.5806608,0.0001820905,0.00006208184,0.00001046093,0.0003354821,0.00325807,0.3841513,0.0002823571,0.002760078,0.001096591],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977505,0.000440958,0.0006800749,0.0000855308,0.00003913657,0.0006116435,0.00005998259,0.00001599497,0.0003162154],"genre_scores_gemma":[0.9984384,0.00004202195,0.0008945871,0.00003354054,0.0000568838,0.00004534723,0.0003017183,0.00002765052,0.0001598711],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3477862,"threshold_uncertainty_score":0.9028944,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03110455564745018,"score_gpt":0.3024169465348727,"score_spread":0.2713123908874225,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}