{"id":"W2185069553","doi":"10.1093/ofid/ofv059","title":"Switch to Raltegravir From Protease Inhibitor or Nonnucleoside Reverse-Transcriptase Inhibitor Does not Reduce Visceral Fat In Human Immunodeficiency Virus-Infected Women With Central Adiposity","year":2015,"lang":"en","type":"article","venue":"Open Forum Infectious Diseases","topic":"HIV-related health complications and treatments","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Center for Advancing Translational Sciences; National Center for Research Resources; Pfizer; National Institute of Mental Health; National Institutes of Health; GlaxoSmithKline; ViiV Healthcare; Gilead Sciences; National Institute of Allergy and Infectious Diseases; Ontario HIV Treatment Network; National Institute on Aging; Bristol-Myers Squibb","keywords":"Raltegravir; Medicine; Adipose tissue; Integrase inhibitor; Virology; Protease inhibitor (pharmacology); Human immunodeficiency virus (HIV); Reverse-transcriptase inhibitor; Lipodystrophy; Reverse transcriptase; Internal medicine; Antiretroviral therapy; Viral load; Polymerase chain reaction; Biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001499317,0.0004828193,0.0007330416,0.0003597738,0.000550496,0.000231971,0.0003134614,0.0001539763,0.0003968949],"category_scores_gemma":[0.0001566414,0.0003292746,0.0000989369,0.0009610931,0.0001153173,0.0005773322,0.0001946982,0.0003957357,0.0001689133],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001452819,"about_ca_system_score_gemma":0.0009004545,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01973686,"about_ca_topic_score_gemma":0.003179588,"domain_scores_codex":[0.9968099,0.0001753451,0.0006747155,0.0008544052,0.0004554468,0.001030209],"domain_scores_gemma":[0.9972442,0.00004968748,0.0002039474,0.0008155067,0.0002622787,0.001424377],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02422635,0.01247192,0.8887113,0.0002215825,0.0004944128,0.0007000326,0.00463947,0.0001106852,0.05368948,0.0003353916,0.01091834,0.003481079],"study_design_scores_gemma":[0.05955131,0.02164082,0.8509513,0.003874129,0.0014229,0.0001756431,0.003524985,0.0001431628,0.03268407,0.001584885,0.02178153,0.002665335],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9898834,0.0001251321,0.00003215117,0.00155205,0.0002602888,0.005234708,0.000951137,0.0002199977,0.001741199],"genre_scores_gemma":[0.9952035,0.00001638061,0.0002147153,0.001338509,0.0001311767,0.001534441,0.0003627118,0.00008315821,0.001115395],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03776002,"threshold_uncertainty_score":0.999916,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01945145735741033,"score_gpt":0.3060172386347823,"score_spread":0.2865657812773719,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}