{"id":"W2185449687","doi":"10.1371/journal.ppat.1005285","title":"Follicular Dendritic Cells Retain Infectious HIV in Cycling Endosomes","year":2015,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":112,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"National Institute of Allergy and Infectious Diseases; Ragon Institute of MGH, MIT and Harvard","keywords":"Follicular dendritic cells; Virology; Human immunodeficiency virus (HIV); In vitro; Endosome; Immunology; Virus; Germinal center; Biology; Receptor; Antigen-presenting cell; Antibody; Immune system; T cell; B cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002165415,0.0001505887,0.0002509971,0.0001683613,0.00007592931,0.00001523869,0.0001204987,0.0001511584,0.0001616279],"category_scores_gemma":[0.0001972234,0.0001316994,0.00007945463,0.0001668559,0.00008365561,0.00005552352,0.0000683777,0.0002451804,0.005643477],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001240002,"about_ca_system_score_gemma":0.00009882285,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005907977,"about_ca_topic_score_gemma":0.00008808988,"domain_scores_codex":[0.9986472,0.000292745,0.000207751,0.0002759884,0.00006139186,0.0005149076],"domain_scores_gemma":[0.9994509,0.0001241201,0.00003604196,0.0002553702,0.0000563499,0.00007726246],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005998176,0.0007184102,0.1185736,0.00002279329,0.0002429873,0.0008425248,0.001059971,0.00004100688,0.8749202,0.0001722442,0.001645244,0.001701024],"study_design_scores_gemma":[0.01106702,0.0008529086,0.009637583,0.000138404,0.0001790823,0.0002724669,0.001084431,0.00009236115,0.9452546,0.001172877,0.02955945,0.0006887789],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920403,0.002530398,0.00004334814,0.0001587063,0.0001609771,0.0003216981,0.0001114398,0.00008103919,0.004552116],"genre_scores_gemma":[0.997655,0.00011033,0.0001154544,0.00005029024,0.00002790474,0.00008257575,0.0001562783,0.00001853076,0.001783611],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.108936,"threshold_uncertainty_score":0.9951307,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02651353892843055,"score_gpt":0.2517356295239483,"score_spread":0.2252220905955177,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}