{"id":"W2185449687","doi":"10.1371/journal.ppat.1005285","title":"Follicular Dendritic Cells Retain Infectious HIV in Cycling Endosomes","year":2015,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":112,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"National Institute of Allergy and Infectious Diseases; Ragon Institute of MGH, MIT and Harvard","keywords":"Follicular dendritic cells; Virology; Human immunodeficiency virus (HIV); In vitro; Endosome; Immunology; Virus; Germinal center; Biology; Receptor; Antigen-presenting cell; Antibody; Immune system; T cell; B cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001528275,0.000147513,0.0002098303,0.0002078447,0.0004312056,0.0005743609,0.0002579275,0.0003424695,0.001027948],"category_scores_gemma":[0.0002076689,0.0000923858,0.0002217889,0.0001659734,0.000229952,0.0003146785,0.0003203349,0.0003795995,0.0004966955],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004308585,"about_ca_system_score_gemma":0.0003777627,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001760707,"about_ca_topic_score_gemma":0.001173811,"domain_scores_codex":[0.9998558,0.00001476698,0.000007383572,0.00003034829,0.00002800093,0.00006370092],"domain_scores_gemma":[0.9999063,0.00001046891,0.00001244441,0.00001934384,0.00002778257,0.00002375635],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001578557,0.00001888879,0.002630008,0.00004398893,0.000009191172,0.0002533908,0.000121842,0.00004660874,0.9891172,0.000389309,0.0002239916,0.006987682],"study_design_scores_gemma":[0.00008970614,0.0009212368,0.04595082,0.00009539111,0.0001039196,0.00441096,0.0008796343,0.001162134,0.8929381,0.001548069,0.05186274,0.00003728323],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9891327,0.004191724,0.002252709,0.0002287251,0.00004951928,0.00003777777,0.0003144944,0.00004927614,0.003743048],"genre_scores_gemma":[0.9953485,0.0008874332,0.0009434654,0.0001106644,0.00002914512,0.00001552072,0.000278965,0.00001069814,0.002375596],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001760707,"threshold_uncertainty_score":0.003500938,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02651353892843055,"score_gpt":0.2517356295239483,"score_spread":0.2252220905955177,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}