{"id":"W2185625431","doi":"","title":"Involvement of Cytochrome P-450 in n-Butyl Nitrite-Induced Hepatocyte Cytotoxicity","year":2005,"lang":"en","type":"article","venue":"Iranian journal of pharmaceutical sciences","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Peroxynitrite; Chemistry; Glutathione; Biochemistry; Nitric oxide; Lipid peroxidation; Cytochrome c; Nitrite; Superoxide; Cytochrome; Reactive oxygen species; Hepatocyte; Oxidative phosphorylation; Mitochondrion; Oxidative stress; Enzyme; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003446535,0.000365414,0.0003694963,0.0002053939,0.000205643,0.0001894511,0.0001328762,0.0002738347,0.0007895074],"category_scores_gemma":[0.0002424207,0.0001381981,0.0002668397,0.0001246786,0.0002394294,0.0001872833,0.0001873046,0.0003642989,0.0001655231],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001590802,"about_ca_system_score_gemma":0.0002206855,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004362198,"about_ca_topic_score_gemma":0.0005610163,"domain_scores_codex":[0.9998017,0.00006779721,0.00002120798,0.00002118744,0.00005021347,0.00003798816],"domain_scores_gemma":[0.9998282,0.00003133934,0.00004281343,0.00002923054,0.00003483257,0.0000335591],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004673566,0.00009292382,0.001006438,0.00008808589,0.00001771629,0.0004091391,0.00003819625,0.00007337075,0.9950789,0.0001069163,0.00003830112,0.002582698],"study_design_scores_gemma":[0.00007225241,0.001604505,0.02498714,0.00001498781,0.00004609321,0.0009647087,0.00005420282,0.000864195,0.9698058,0.0002360115,0.001341804,0.000008241563],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882576,0.005683732,0.003867452,0.000180723,0.00007075343,0.0000773687,0.0001250587,0.00005332927,0.001683797],"genre_scores_gemma":[0.9963832,0.001328919,0.0009574581,0.00004226058,0.00002167858,0.00004213185,0.0001274334,0.000004444452,0.00109241],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007895074,"threshold_uncertainty_score":0.002641141,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08084787472516315,"score_gpt":0.3820785692447868,"score_spread":0.3012306945196237,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}