{"id":"W2186359677","doi":"10.1371/journal.pone.0143589","title":"Can CD44 Be a Mediator of Cell Destruction? The Challenge of Type 1 Diabetes","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Proteoglycans and glycosaminoglycans research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Office of Science","keywords":"Internal medicine; Endocrinology; Insulin resistance; CD44; Biology; Nod; Insulin; NOD mice; Pancreatic islets; Cell biology; Cell; Cancer research; Diabetes mellitus; Islet; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004116301,0.0003188079,0.0003825351,0.0002106387,0.0001393824,0.0005502824,0.0002168966,0.0007053158,0.001253113],"category_scores_gemma":[0.0003329412,0.00007091498,0.0002530227,0.0001540431,0.0003405107,0.0005958481,0.0003443593,0.001000378,0.0002485325],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001772866,"about_ca_system_score_gemma":0.000121624,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008686111,"about_ca_topic_score_gemma":0.0000861341,"domain_scores_codex":[0.9998068,0.00005618214,0.00001021848,0.000025353,0.00003774377,0.0000636437],"domain_scores_gemma":[0.9998778,0.00002775533,0.00003095256,0.00001219618,0.00001414198,0.00003701654],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002123374,0.0006408472,0.01086403,0.002338927,0.0001025778,0.002695832,0.0003304047,0.0002862568,0.8278092,0.007098333,0.002479842,0.1432305],"study_design_scores_gemma":[0.0004010364,0.01205557,0.1668274,0.001144679,0.0006121196,0.01282893,0.001526421,0.003038072,0.5984799,0.011155,0.1918404,0.00009042223],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8431981,0.1339149,0.004029324,0.007129766,0.001200085,0.00008254102,0.0001723097,0.00007959049,0.01019343],"genre_scores_gemma":[0.9511431,0.04132577,0.00114252,0.001264564,0.0008335157,0.00005412776,0.0001056008,0.00001128145,0.004119476],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001253113,"threshold_uncertainty_score":0.004192054,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05148085507260126,"score_gpt":0.2542072126133678,"score_spread":0.2027263575407666,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}