{"id":"W2186695811","doi":"10.1016/j.bbrc.2015.11.128","title":"MiR-486 regulates cholesterol efflux by targeting HAT1","year":2015,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":false,"ca_institutions":"Libin Cardiovascular Institute of Alberta; University of Calgary","funders":"National Natural Science Foundation of China; National Science Foundation","keywords":"ABCA1; Transfection; Acetyltransferase; Molecular biology; Untranslated region; Downregulation and upregulation; Messenger RNA; Luciferase; Acetylation; Biology; Chemistry; Cell biology; Biochemistry; Transporter; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000190799,0.0003058396,0.0002742096,0.0002599685,0.0004076631,0.0006037269,0.0002698417,0.000336167,0.00435764],"category_scores_gemma":[0.0003119992,0.0002874577,0.0003714118,0.0001426432,0.0003122572,0.0003115471,0.0002955097,0.000848901,0.001621348],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005035165,"about_ca_system_score_gemma":0.0002902989,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009026044,"about_ca_topic_score_gemma":0.001392968,"domain_scores_codex":[0.9997862,0.00002716558,0.00001697596,0.00005113083,0.0000596278,0.00005905373],"domain_scores_gemma":[0.9999039,0.00001513602,0.00002551227,0.0000112746,0.00001937515,0.0000247431],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006465482,0.00005356453,0.001655688,0.00007549179,0.00003585054,0.000176188,0.00004042665,0.0001532454,0.9869462,0.0009238732,0.001276116,0.008016877],"study_design_scores_gemma":[0.00008825622,0.0001774599,0.01097404,0.00001106597,0.00006965275,0.0004651333,0.00009562843,0.003193426,0.9665258,0.0004221771,0.01796033,0.00001695489],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9651401,0.005901856,0.009598414,0.001291222,0.0005792422,0.00005352513,0.001394158,0.000976257,0.01506518],"genre_scores_gemma":[0.9908453,0.0008437497,0.001699534,0.0001870146,0.00003443387,0.00002483035,0.0005223588,0.00006769289,0.005774978],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00435764,"threshold_uncertainty_score":0.01457775,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1106814120857848,"score_gpt":0.3916813167227877,"score_spread":0.2809999046370029,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}