{"id":"W2186740209","doi":"10.2310/7290.2007.00020","title":"In Vivo Resolution of Multiexponential Decays of Multiple Near-Infrared Molecular Probes by Fluorescence Lifetime-Gated Whole-Body Time-Resolved Diffuse Optical Imaging","year":2007,"lang":"en","type":"article","venue":"Molecular Imaging","topic":"Photodynamic Therapy Research Studies","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"Polytechnique Montréal","funders":"National Institute of Biomedical Imaging and Bioengineering; National Cancer Institute","keywords":"Fluorescence; Fluorophore; Biodistribution; Chemistry; Fluorescence-lifetime imaging microscopy; Whole body imaging; In vivo; Preclinical imaging; Autofluorescence; Nuclear magnetic resonance; Biophysics; Optics; Positron emission tomography; Nuclear medicine; Physics; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009776803,0.0003819024,0.0007576277,0.0004363185,0.00009529001,0.00003603051,0.0003342862,0.00009883042,0.00004127168],"category_scores_gemma":[0.001067713,0.0003865291,0.0002381018,0.0006693186,0.0007542951,0.0002158253,0.0002937707,0.0004654276,0.000008923994],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002181484,"about_ca_system_score_gemma":0.0001597776,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005301397,"about_ca_topic_score_gemma":0.000007273151,"domain_scores_codex":[0.9963404,0.0001466891,0.0009617311,0.0006216654,0.001007236,0.0009222824],"domain_scores_gemma":[0.9982451,0.000200308,0.0002501311,0.0006485032,0.0003881495,0.0002678447],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001255709,0.0008149025,0.005602838,0.000153087,0.0001371665,0.0008114116,0.0004868471,0.00009587402,0.9885975,0.0000147705,0.0005403834,0.001489506],"study_design_scores_gemma":[0.005979052,0.0001109775,0.003315805,0.0004264424,0.00007268426,0.00003132958,0.0001341116,0.1272118,0.8621084,0.00003400698,0.0003034333,0.0002719782],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9651505,0.001901742,0.03040124,0.0007662911,0.00006381251,0.001205884,0.00005441804,0.00009095034,0.0003651681],"genre_scores_gemma":[0.9887384,0.00002955969,0.01074153,0.0001772087,0.00002233524,0.00002760484,0.00006547814,0.00008396003,0.0001139861],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1271159,"threshold_uncertainty_score":0.9998587,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005173092504673331,"score_gpt":0.2668246924862827,"score_spread":0.2616515999816094,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}