{"id":"W2187898585","doi":"10.1038/ncomms10013","title":"MLLT1 YEATS domain mutations in clinically distinctive Favourable Histology Wilms tumours","year":2015,"lang":"en","type":"article","venue":"Nature Communications","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":97,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre","funders":"BC Cancer Agency; IDP Foundation; King Abdullah University of Science and Technology; Children’s Oncology Group; Canada's Michael Smith Genome Sciences Centre; National Cancer Institute; National Institutes of Health; U.S. Department of Health and Human Services","keywords":"Wilms' tumor; Mutant; Hox gene; Mutation; Biology; Wilms tumour; Histone; Gene; Cancer research; Kidney development; Genetics; Pathology; Gene expression; Medicine; Embryonic stem cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001491711,0.0002770878,0.0002112981,0.0007642061,0.0001872767,0.0002953184,0.0001882802,0.0004753173,0.001792894],"category_scores_gemma":[0.0007247063,0.0001291261,0.0001741958,0.0003440288,0.0004904505,0.0001675731,0.0003463466,0.0001631237,0.0002235378],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002144148,"about_ca_system_score_gemma":0.0001827031,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000647245,"about_ca_topic_score_gemma":0.001041453,"domain_scores_codex":[0.999894,0.00001234345,0.00001101411,0.00002396749,0.00003081072,0.0000279668],"domain_scores_gemma":[0.9995444,0.00007912288,0.0001561599,0.00001392969,0.00002451959,0.0001817169],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001871055,0.00005141155,0.4723408,0.0001561723,0.00006595458,0.1827096,0.0005465019,0.0008915034,0.3272949,0.0008578043,0.0007423323,0.01247192],"study_design_scores_gemma":[0.0000568031,0.000284747,0.7936187,0.00001781463,0.00006230965,0.1852519,0.0003065952,0.0008679212,0.01764783,0.0006538998,0.001203301,0.00002816611],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986337,0.0001759999,0.0001447826,0.00003804128,0.000006110299,0.000006648987,0.00007451539,0.0000147239,0.0009056353],"genre_scores_gemma":[0.999699,0.00005279026,0.00009565884,0.000007256242,0.000006729956,0.000001103687,0.00003287843,0.000003096844,0.0001015874],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001792894,"threshold_uncertainty_score":0.005997896,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0192797465195592,"score_gpt":0.3208865380305441,"score_spread":0.3016067915109849,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}