{"id":"W2187911599","doi":"10.1681/asn.2015020139","title":"Integrin-linked Kinase Controls Renal Branching Morphogenesis via Dual Specificity Phosphatase 8","year":2015,"lang":"en","type":"article","venue":"Journal of the American Society of Nephrology","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; Canada Research Chairs; Sick Kids Foundation","keywords":"Integrin-linked kinase; Kidney development; Cell biology; Ureteric bud; Biology; Morphogenesis; Kinase; Protein kinase A; Embryonic stem cell; Molecular biology; Cyclin-dependent kinase 2; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008475938,0.0003160784,0.0001699902,0.0002246553,0.0001672915,0.0003141889,0.0001305839,0.0001684006,0.0006094391],"category_scores_gemma":[0.00009671671,0.0001651945,0.0002455757,0.0001371112,0.0001924054,0.0002146989,0.0002530914,0.0003895563,0.0002013168],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003630418,"about_ca_system_score_gemma":0.0002024487,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004517227,"about_ca_topic_score_gemma":0.0007461105,"domain_scores_codex":[0.9998469,0.00002479604,0.0000113563,0.00003985719,0.00003409693,0.0000429222],"domain_scores_gemma":[0.9999007,0.000007969982,0.00004213869,0.000006796146,0.00001133378,0.00003097523],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003304968,0.00000509749,0.000289039,0.00001163403,0.000001479999,0.00002667821,0.000008826341,0.00002541413,0.9991161,0.00005964145,0.00001100648,0.0004121422],"study_design_scores_gemma":[0.00001957107,0.0001091956,0.02543072,0.000005411566,0.00001967189,0.0003341358,0.00006150894,0.001581154,0.970198,0.0001128368,0.002120339,0.000007572799],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950982,0.001180324,0.00233807,0.00005689125,0.00001057413,0.00001037206,0.0001559847,0.00006278793,0.00108687],"genre_scores_gemma":[0.9968003,0.0005816069,0.001019549,0.0000259192,0.000004980793,0.00001427996,0.0001728391,0.00001009329,0.001370294],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006094391,"threshold_uncertainty_score":0.002634048,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01391372424114106,"score_gpt":0.2512426198569424,"score_spread":0.2373288956158013,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}