{"id":"W2188324213","doi":"10.1152/ajplung.2001.281.1.l217","title":"Modulation of α-ENaC and α<sub>1</sub>-Na<sup>+</sup>-K<sup>+</sup>-ATPase by cAMP and dexamethasone in alveolar epithelial cells","year":2001,"lang":"en","type":"article","venue":"American Journal of Physiology-Lung Cellular and Molecular Physiology","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":106,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôtel-Dieu de Montréal; Ottawa Hospital; Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"Epithelial sodium channel; Dexamethasone; Messenger RNA; Internal medicine; Endocrinology; Molecular biology; Downregulation and upregulation; Chloramphenicol acetyltransferase; Chemistry; Gene expression; Biology; Reporter gene; Gene; Medicine; Biochemistry; Sodium","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001199517,0.000299128,0.0003286726,0.0001346493,0.0001396853,0.000397681,0.0001832821,0.0002549661,0.0007597784],"category_scores_gemma":[0.0001570237,0.0001332537,0.0002752912,0.0001426131,0.0002584777,0.0002755567,0.0001671904,0.0005249835,0.0002990655],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002992649,"about_ca_system_score_gemma":0.000214407,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007767821,"about_ca_topic_score_gemma":0.001166789,"domain_scores_codex":[0.9997813,0.00003856934,0.00002882886,0.00004054541,0.00005437561,0.0000564432],"domain_scores_gemma":[0.9998479,0.00003515833,0.00003112201,0.00001995318,0.00003048744,0.00003537273],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001852955,0.00001577086,0.0002067562,0.00004185588,0.000003353406,0.00005221717,0.0000177781,0.00002318785,0.9985788,0.00003034325,0.00001107291,0.000833639],"study_design_scores_gemma":[0.00002059179,0.0004634524,0.01047355,0.000009966543,0.00001705817,0.000237452,0.0001626452,0.0002940457,0.9860324,0.00004704605,0.002236276,0.000005428999],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988787,0.008109072,0.001303102,0.0001242812,0.00007749848,0.00003186567,0.000350294,0.00002628358,0.001190588],"genre_scores_gemma":[0.9926119,0.003370189,0.00151254,0.0000849191,0.00002999746,0.00005707411,0.0004846509,0.000008844816,0.001839872],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007767821,"threshold_uncertainty_score":0.002541721,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003175424774167608,"score_gpt":0.1994791471772037,"score_spread":0.1963037224030361,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}