{"id":"W2188661282","doi":"10.1101/gad.266056.115","title":"REC-1 and HIM-5 distribute meiotic crossovers and function redundantly in meiotic double-strand break formation in <i>Caenorhabditis elegans</i>","year":2015,"lang":"en","type":"article","venue":"Genes & Development","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; Wellcome; Canadian Institutes of Health Research; Eunice Kennedy Shriver National Institute of Child Health and Human Development; University of British Columbia; Wellcome Trust; Francis Crick Institute; European Research Council; National Institutes of Health; Cancer Research UK; Magee-Womens Research Institute; Medical Research Council","keywords":"Biology; Caenorhabditis elegans; Genetics; Meiosis; Genetic screen; Bivalent (engine); Cyclin-dependent kinase; Chromosomal crossover; Gene; Mutant; Cell biology; Cell cycle","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009263219,0.0003457239,0.0001722382,0.0002203305,0.0002302802,0.0003611556,0.0003358422,0.0002609862,0.0006395588],"category_scores_gemma":[0.0001141294,0.0002979306,0.0001689293,0.00007401876,0.0002463947,0.0001915843,0.0003113612,0.0003293445,0.0002739336],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004434505,"about_ca_system_score_gemma":0.0002612202,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00127142,"about_ca_topic_score_gemma":0.00299832,"domain_scores_codex":[0.999879,0.000008361972,0.000009624184,0.00004153461,0.000032861,0.00002854806],"domain_scores_gemma":[0.9998648,0.00001055483,0.00005298363,0.00001613224,0.000009431316,0.00004605427],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006861263,0.000008452663,0.000467433,0.00001461894,0.000003422093,0.00006433149,0.000007827208,0.00008078077,0.9983491,0.0001397197,0.00001631671,0.0007794028],"study_design_scores_gemma":[0.00002213319,0.00009642886,0.02527894,0.000007191758,0.00001930362,0.0006318688,0.00004729417,0.001689067,0.9701147,0.0001025321,0.001979968,0.00001069999],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974532,0.0006003502,0.001049928,0.00003254274,0.000008537393,0.000004834454,0.00008929496,0.00004460856,0.0007167471],"genre_scores_gemma":[0.9969375,0.0001792158,0.001296757,0.00002078813,0.000002315304,0.000004655025,0.0001397112,0.00001501354,0.001404193],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00127142,"threshold_uncertainty_score":0.003217399,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01508656677814204,"score_gpt":0.2214306179663962,"score_spread":0.2063440511882541,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}