{"id":"W2188767859","doi":"","title":"Antiproliferative effects of a series of novel synthetic sulfonate esters on human breast cancer cell line MCF-7.","year":2007,"lang":"en","type":"article","venue":"PubMed","topic":"Enzyme function and inhibition","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Moncton","funders":"","keywords":"MCF-7; Cancer cell; Apoptosis; Chemistry; Cell culture; Cancer research; Cancer; Breast cancer; Human breast; IC50; Growth inhibition; Cell growth; In vitro; Cell cycle; Cell cycle checkpoint; Pharmacology; Biochemistry; Internal medicine; Medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001378404,0.00009410807,0.0001185711,0.00003294438,0.00002749928,0.000003867649,0.00004899301,0.00007758674,0.000009951631],"category_scores_gemma":[0.00002452539,0.00008339876,0.00005635403,0.00005498256,0.00007348724,0.000005202369,0.00002220801,0.00004164936,3.65601e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001529496,"about_ca_system_score_gemma":0.00001278564,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003722102,"about_ca_topic_score_gemma":0.00007074419,"domain_scores_codex":[0.9993993,0.00001710217,0.0001694992,0.0001617921,0.00009167822,0.0001606039],"domain_scores_gemma":[0.999611,0.00001257401,0.000112093,0.0001337194,0.00008151848,0.00004905165],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003671535,0.000273809,0.001115766,0.0001145341,0.000031106,8.040968e-7,0.00004026773,0.00004998482,0.995156,0.0001546304,0.000239485,0.002456388],"study_design_scores_gemma":[0.0007606712,0.0002042366,0.06113509,0.00002818513,0.00001583464,0.000004640799,0.0000263395,0.000003350659,0.9373614,0.000004604224,0.0003754671,0.00008017918],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996663,0.0001497057,0.0003414285,0.00007232116,0.0001574055,0.0002999333,0.00004840382,0.00000651163,0.002261267],"genre_scores_gemma":[0.9988809,0.00005858298,0.0000285614,0.0001579373,0.0001037192,0.00009281227,0.00002974908,0.00001174309,0.0006359992],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06001933,"threshold_uncertainty_score":0.3400903,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01361351599354169,"score_gpt":0.2403728166740078,"score_spread":0.2267593006804661,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}