{"id":"W2189098641","doi":"10.1016/s0898-6568(01)00259-5","title":"G protein specificity","year":2002,"lang":"en","type":"review","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":168,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"G protein; Receptor; G protein-coupled receptor; Pertussis toxin; Cell biology; Effector; Signal transduction; Biology; G beta-gamma complex; G alpha subunit; Protein subunit; Scaffold protein; Heterotrimeric G protein; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003456043,0.0005678121,0.001004464,0.0001033805,0.000145388,0.0000898914,0.0005168282,0.0007101404,0.0009826638],"category_scores_gemma":[0.00003391789,0.0005090039,0.0008174354,0.0001634546,0.00004197935,0.000002693373,0.0001482288,0.0004047928,0.0002943307],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003656391,"about_ca_system_score_gemma":0.00009533948,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000191159,"about_ca_topic_score_gemma":5.018739e-7,"domain_scores_codex":[0.9976564,0.0001837247,0.000622339,0.0008232158,0.0002510116,0.0004633285],"domain_scores_gemma":[0.998897,0.00001433073,0.00033627,0.000536391,0.00006367469,0.0001523172],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000005468797,0.00008069318,9.711491e-8,0.004781941,0.0002489822,0.00005334695,0.00001994951,0.00001578356,0.1896465,0.0001906981,0.0005860183,0.8043705],"study_design_scores_gemma":[0.00008311376,0.00008651346,1.520315e-9,0.002700307,0.000158902,0.00001245625,0.000005164104,0.000034622,0.05396813,0.00006747105,0.9423193,0.0005639632],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007814805,0.9771325,0.02050291,0.000001756773,0.0002778182,0.0007663907,0.00001837209,0.00003366129,0.001188416],"genre_scores_gemma":[0.0001299074,0.9915208,0.001581,0.00001326496,0.001500518,0.0001017472,0.0004351756,0.0001500889,0.004567549],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9417334,"threshold_uncertainty_score":0.9999306,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04483234947529639,"score_gpt":0.2644662048778399,"score_spread":0.2196338554025435,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}