{"id":"W2190070911","doi":"10.1039/c5ib90052b","title":"Getting there is half the battle: recent advances in delivering therapeutics","year":2015,"lang":"en","type":"review","venue":"Integrative Biology","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Battle; Focus (optics); Medicine; Engineering ethics; Engineering; Geography; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001027135,0.0009044489,0.001140495,0.002102691,0.0003947464,0.001316841,0.0009344372,0.0013727,0.002919207],"category_scores_gemma":[0.000928055,0.0003337039,0.0004296082,0.002241809,0.0008956306,0.002466802,0.0009563307,0.002623006,0.001863742],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007903102,"about_ca_system_score_gemma":0.001013165,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006438721,"about_ca_topic_score_gemma":0.00106624,"domain_scores_codex":[0.9996992,0.00005066102,0.00003532775,0.00005362283,0.0001247491,0.0000364851],"domain_scores_gemma":[0.999499,0.0002648106,0.00005254736,0.00001659074,0.0001117922,0.00005529482],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007464121,0.00009644923,0.0001611706,0.02018006,0.00007388279,0.0002454738,0.0001736285,0.0005574246,0.005893779,0.01485387,0.03081386,0.9268757],"study_design_scores_gemma":[0.000007004673,0.00007576079,0.0002941582,0.001485855,0.00005019445,0.0007458147,0.00008241407,0.00009552278,0.0009464773,0.003429503,0.9927658,0.00002145917],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001254596,0.9980928,0.0003141957,0.0004336997,0.0002729718,0.000002613642,0.000006781181,0.000009371167,0.0007420463],"genre_scores_gemma":[0.0007663633,0.9978962,0.0003631067,0.0002367736,0.0002396089,0.000004201263,0.00001342783,0.000002479305,0.0004779335],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002919207,"threshold_uncertainty_score":0.009765685,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06518470747035045,"score_gpt":0.3827540675503955,"score_spread":0.317569360080045,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}