{"id":"W2190521646","doi":"10.1016/j.trecan.2015.09.002","title":"Modeling Normal and Disordered Human Hematopoiesis","year":2015,"lang":"en","type":"review","venue":"Trends in cancer","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency","funders":"Terry Fox Foundation; Diamond Blackfan Anemia Foundation","keywords":"Haematopoiesis; Biology; Epigenetics; Phenotype; Blood cell; Human blood; Cell biology; Stem cell; Gene; Genetics; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007098084,0.001019966,0.001399268,0.0006711144,0.0001778479,0.0009761643,0.001465876,0.001090819,0.00173755],"category_scores_gemma":[0.001524524,0.0003271443,0.0005556054,0.0007321474,0.0007054355,0.001553884,0.0007684215,0.001331233,0.0007113446],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009174139,"about_ca_system_score_gemma":0.001694335,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002971826,"about_ca_topic_score_gemma":0.003373183,"domain_scores_codex":[0.9998584,0.00003764258,0.00001170851,0.00002561225,0.00005406288,0.00001255924],"domain_scores_gemma":[0.9996399,0.0002174991,0.00003542366,0.00001924684,0.00006236249,0.00002569805],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006413995,0.00007288026,0.0008874706,0.008876196,0.00017928,0.0001566778,0.00006942065,0.04387062,0.002468108,0.05908394,0.03175602,0.8525152],"study_design_scores_gemma":[0.000044088,0.0001028853,0.0008048663,0.004302003,0.0003765611,0.0007178968,0.00009913691,0.05002378,0.00315514,0.1292128,0.8110851,0.00007587778],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000988369,0.9793911,0.01453403,0.001207844,0.000587963,0.00001038505,0.00007989501,0.0001042043,0.00309625],"genre_scores_gemma":[0.01041815,0.9808125,0.006250166,0.0004657508,0.0004874409,0.00001949794,0.0001595248,0.00001789394,0.001369079],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002971826,"threshold_uncertainty_score":0.006656349,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1464639320753998,"score_gpt":0.4311040994055195,"score_spread":0.2846401673301198,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}