{"id":"W2190843185","doi":"10.1016/j.cjca.2015.10.012","title":"Effects of Iron Overload on Cardiac Calcium Regulation: Translational Insights Into Mechanisms and Management of a Global Epidemic","year":2015,"lang":"en","type":"review","venue":"Canadian Journal of Cardiology","topic":"Hemoglobinopathies and Related Disorders","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Medicine; Cardiomyopathy; Calcium; Calcium in biology; Internal medicine; Cardiac function curve; Hemoglobinopathy; Heart failure; Cardiology; Endocrinology; Hemolytic anemia","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008822915,0.0006947761,0.001609641,0.002050848,0.0003688907,0.001099604,0.0008765457,0.001247593,0.003113837],"category_scores_gemma":[0.001533621,0.0001888754,0.0004937007,0.001777176,0.0007150787,0.0008803449,0.0007322587,0.001651065,0.0006877545],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009551821,"about_ca_system_score_gemma":0.002710103,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005830492,"about_ca_topic_score_gemma":0.01301261,"domain_scores_codex":[0.9998067,0.00003144117,0.00003226358,0.00003173882,0.00007486669,0.00002293508],"domain_scores_gemma":[0.9991301,0.0004838847,0.00009185124,0.00001376863,0.0002160796,0.00006442604],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001572879,0.00008864927,0.0006008292,0.01841245,0.0001776256,0.0002800034,0.00009472841,0.0002745345,0.0007864886,0.003947358,0.03940336,0.9357768],"study_design_scores_gemma":[0.00007975862,0.0001344196,0.003804986,0.01289367,0.0005100165,0.001417596,0.0002300882,0.0002404623,0.0003591648,0.005094859,0.9751881,0.0000468344],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007286363,0.9989128,0.00004578431,0.0005139375,0.0001350252,0.000001925508,0.00001059251,0.000003088945,0.0003039968],"genre_scores_gemma":[0.0005943564,0.9987192,0.00009173252,0.0002131698,0.0002569428,0.000002207501,0.00001282957,5.103794e-7,0.0001089961],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005830492,"threshold_uncertainty_score":0.0115931,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01895005756993741,"score_gpt":0.2868597426903172,"score_spread":0.2679096851203798,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}