{"id":"W2190901406","doi":"10.1016/j.ebiom.2015.12.004","title":"Small CD4 Mimetics Prevent HIV-1 Uninfected Bystander CD4 + T Cell Killing Mediated by Antibody-dependent Cell-mediated Cytotoxicity","year":2015,"lang":"en","type":"article","venue":"EBioMedicine","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":78,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute; McGill University Health Centre; Université de Montréal; McGill University; Centre Hospitalier de l’Université de Montréal; Université du Québec à Montréal","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; National Institutes of Health; Canada Foundation for Innovation","keywords":"Bystander effect; Cytotoxicity; Antibody; Immunology; Cell; Human immunodeficiency virus (HIV); Medicine; Virology; Biology; In vitro; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009812298,0.0002452462,0.0002681004,0.0001566991,0.0001173879,0.000211202,0.0002030758,0.0002578328,0.001450038],"category_scores_gemma":[0.000162791,0.0001039069,0.00009571409,0.00004976258,0.0001908508,0.0001969888,0.000147005,0.0004663068,0.0002873492],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001713095,"about_ca_system_score_gemma":0.000115034,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001315428,"about_ca_topic_score_gemma":0.0001891847,"domain_scores_codex":[0.9999425,0.00001416171,0.000003602933,0.00000706636,0.00001523995,0.00001739364],"domain_scores_gemma":[0.9999583,0.00001396827,0.000008622475,0.000004531448,0.000003751365,0.00001094865],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008364836,0.0004456088,0.0002534595,0.0001143248,0.00001434054,0.0001451659,0.00003351951,0.0003797475,0.9775565,0.0006526823,0.000488036,0.01908007],"study_design_scores_gemma":[0.0004091999,0.004196058,0.001836903,0.00001513501,0.00003035028,0.0004625139,0.00001933652,0.001756593,0.9830137,0.0003847703,0.007868328,0.000007108503],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925964,0.00284951,0.001771307,0.0001425606,0.00006753108,0.00006544931,0.00006472845,0.0001242958,0.002318138],"genre_scores_gemma":[0.9942154,0.001284208,0.001268488,0.0001141283,0.00003425861,0.0000415703,0.00009504834,0.000009219604,0.002937585],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001450038,"threshold_uncertainty_score":0.004850864,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02066073535279104,"score_gpt":0.2630193434613716,"score_spread":0.2423586081085805,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}