{"id":"W2191306486","doi":"10.1016/j.mce.2015.12.002","title":"Recombinant Reg3α protein protects against experimental acute pancreatitis in mice","year":2015,"lang":"en","type":"article","venue":"Molecular and Cellular Endocrinology","topic":"Pancreatitis Pathology and Treatment","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"Fundamental Research Funds for the Central Universities; Priority Academic Program Development of Jiangsu Higher Education Institutions; Government of Jiangsu Province","keywords":"Downregulation and upregulation; Apoptosis; Poly ADP ribose polymerase; Molecular biology; Biology; Cyclin D1; Neogenesis; Acinar cell; Protein kinase B; Pancreas; Cancer research; Chemistry; Endocrinology; Biochemistry; Polymerase; Cell cycle; Enzyme; Islet; Gene; Insulin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008266755,0.0002286273,0.0004403819,0.0001487867,0.00004690138,0.000009215883,0.00006612587,0.0001435179,0.00001659282],"category_scores_gemma":[0.00003614783,0.0002085178,0.00006677627,0.000117989,0.0001527905,0.0000445983,0.00008388115,0.0002432334,0.00004709836],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001056734,"about_ca_system_score_gemma":0.00008722826,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001314625,"about_ca_topic_score_gemma":0.00001077215,"domain_scores_codex":[0.9985493,0.0001737433,0.0002385847,0.0004438071,0.0001279696,0.000466613],"domain_scores_gemma":[0.99944,0.000008769222,0.00005717146,0.0002662284,0.00003791651,0.0001899592],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003849259,0.0005567813,0.009237327,0.00003286663,0.0001815331,0.05187027,0.000369622,0.000001436547,0.9317203,0.003201881,0.00006564893,0.002377379],"study_design_scores_gemma":[0.005931118,0.001449196,0.001405205,0.00007820928,0.00007538682,0.00265037,0.0001602224,0.00002341157,0.9862298,0.0005194157,0.001270011,0.0002076252],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9851189,0.005807391,0.0002234459,0.0004676739,0.0001055142,0.001044228,0.000003992112,0.00006032058,0.007168517],"genre_scores_gemma":[0.9966078,0.0001045154,0.001511556,0.0002963514,0.00002033594,0.0004449858,0.00006563697,0.00002668395,0.0009220698],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0545095,"threshold_uncertainty_score":0.8503108,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01439914204976782,"score_gpt":0.2545642784740067,"score_spread":0.2401651364242389,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}