{"id":"W2191824595","doi":"10.3390/fermentation1010113","title":"Antisense-RNA-Mediated Gene Downregulation in Clostridium pasteurianum","year":2015,"lang":"en","type":"article","venue":"Fermentation","topic":"Microbial Fuel Cells and Bioremediation","field":"Environmental Science","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centurion Biofuels (Canada); University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Gene knockdown; Biology; Antisense RNA; Hydrogenase; Gene; Gene expression; Plasmid; Promoter; Downregulation and upregulation; Regulation of gene expression; Molecular biology; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002638461,0.0005037414,0.0002661831,0.0001453559,0.0001766624,0.0002797463,0.0003006287,0.0003862316,0.0006385929],"category_scores_gemma":[0.0001983054,0.0002082181,0.000336126,0.000138986,0.0002494755,0.0001204648,0.0002442163,0.0007179059,0.0002723036],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004437507,"about_ca_system_score_gemma":0.0004063565,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001836002,"about_ca_topic_score_gemma":0.002250704,"domain_scores_codex":[0.9997236,0.0000290246,0.00002840242,0.00008528,0.00008435312,0.00004934488],"domain_scores_gemma":[0.9998273,0.00003513353,0.00006128525,0.00001848655,0.00003662439,0.00002121716],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001710388,0.000004754553,0.0000233231,0.00001991083,0.000001310407,0.00000595435,0.000005066232,0.00004368546,0.999545,0.00002432195,0.00001341401,0.0002960322],"study_design_scores_gemma":[0.00000908346,0.0002254595,0.0009637715,0.00000335629,0.00001333895,0.00004679411,0.00001241697,0.0006915778,0.9959942,0.00001531594,0.002019496,0.000005091405],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9745474,0.001243547,0.01985183,0.0003091094,0.0001596547,0.0001438408,0.001376644,0.0004276822,0.00194037],"genre_scores_gemma":[0.9733056,0.001336457,0.01704142,0.0002441705,0.00003047302,0.0002019644,0.002124625,0.0001311455,0.005584034],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001836002,"threshold_uncertainty_score":0.003650606,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01777252621691261,"score_gpt":0.2225082396235271,"score_spread":0.2047357134066145,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}