{"id":"W2193169293","doi":"10.12688/f1000research.6529.2","title":"Amicon-adapted enhanced FASP: an in-solution digestion-based alternative sample preparation method to FASP","year":2015,"lang":"en","type":"preprint","venue":"F1000Research","topic":"Advanced Proteomics Techniques and Applications","field":"Chemistry","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Mitacs; Université de Sherbrooke","keywords":"Chromatography; Proteome; Sample preparation; Trypsin; Sample (material); Chemistry; Sodium dodecyl sulfate; Digestion (alchemy); Computational biology; Biology; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001173499,0.0003879242,0.0004448844,0.0003928262,0.0001529241,0.0001491409,0.001000344,0.0005209178,0.0002917416],"category_scores_gemma":[0.00059872,0.0004388356,0.000101655,0.0004224373,0.00008330996,0.0001731483,0.0007081076,0.00134496,0.00005403008],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001278979,"about_ca_system_score_gemma":0.000706288,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003686147,"about_ca_topic_score_gemma":0.0006272838,"domain_scores_codex":[0.9965875,0.0002476623,0.0006026569,0.001203965,0.0007615492,0.0005966561],"domain_scores_gemma":[0.9967797,0.0004451245,0.0002541296,0.001332814,0.0008293575,0.0003588503],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006898363,0.0005057386,0.0003504655,0.0002392923,0.00004336818,0.000005675856,0.001030285,0.1257534,0.8446431,0.003493143,0.0005875791,0.02265809],"study_design_scores_gemma":[0.0004569927,0.0001180554,0.00008234322,0.0002266401,0.00001239832,8.317534e-7,0.00008964214,0.189687,0.7620501,0.04372458,0.003062107,0.0004893129],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.1245123,0.00004068908,0.8685454,0.000521046,0.00004903854,0.001750489,0.0007146515,0.0003786724,0.003487693],"genre_scores_gemma":[0.5992144,0.00003051352,0.3933147,0.00005379096,0.0002308751,0.00421659,0.002381459,0.00008355297,0.0004740363],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.4752307,"threshold_uncertainty_score":0.9998063,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08343363931518878,"score_gpt":0.4464955371363363,"score_spread":0.3630618978211475,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}