{"id":"W2193535549","doi":"10.1038/npp.2015.356","title":"Double Dissociation of Monoacylglycerol Lipase Inhibition and CB1 Antagonism in the Central Amygdala, Basolateral Amygdala, and the Interoceptive Insular Cortex on the Affective Properties of Acute Naloxone-Precipitated Morphine Withdrawal in Rats","year":2015,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"National Institute on Drug Abuse; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health","keywords":"AM251; Monoacylglycerol lipase; Basolateral amygdala; Amygdala; Pharmacology; Cannabinoid receptor; Cannabinoid; Morphine; Taste aversion; Chemistry; (+)-Naloxone; Psychology; Antagonist; Endocannabinoid system; Neuroscience; Receptor; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002074544,0.0009826064,0.0008611361,0.0005339434,0.0003630714,0.000545573,0.0004474459,0.0006144436,0.003676241],"category_scores_gemma":[0.0004022806,0.0006791218,0.0004864905,0.0002465862,0.001283058,0.001088643,0.0004348358,0.002166358,0.0005688372],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008469663,"about_ca_system_score_gemma":0.001137783,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002917969,"about_ca_topic_score_gemma":0.01085259,"domain_scores_codex":[0.9996817,0.00003042164,0.00001546756,0.00005260993,0.00006224508,0.0001576318],"domain_scores_gemma":[0.9995727,0.0000542937,0.00008069011,0.00006515841,0.00004031392,0.0001868808],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01295268,0.0005348473,0.0004055954,0.00007935789,0.00003638147,0.00009673373,0.00009553228,0.000139426,0.9813647,0.0005194657,0.0001103153,0.003664974],"study_design_scores_gemma":[0.0009050365,0.005547226,0.02521744,0.00003105664,0.0001072983,0.0001777223,0.0002942941,0.001345203,0.9647117,0.0005720354,0.001039896,0.00005099122],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978574,0.000386367,0.0003750444,0.0001693719,0.00003641316,0.00002108136,0.0002611337,0.00003239667,0.00086083],"genre_scores_gemma":[0.9919322,0.0009035663,0.0007161386,0.0001375389,0.00003087143,0.0001047347,0.0004548871,0.00003148239,0.005688635],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003676241,"threshold_uncertainty_score":0.01229823,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01956009442425756,"score_gpt":0.2923123839961894,"score_spread":0.2727522895719318,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}